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- W4627269 abstract "The knowledge accumulated in the last few years on the regulation of T cell growth is a good example of the transformation of a field from its infancy to a highly advanced state as the result of the application of modern biotechnologies. Following the discovery of T cell growth factor, or interleukin 2 (IL2), it became possible to clone and establish long-term lines of functional T cells. The field was further advanced with the establishment of a sensitive IL2 bioassay, and the identification of T cell leuke- mias and hybridomas secreting large quantities of IL2 (and other lymphokines). Finally, the application of monoclonal hybridoma technology, modern purification methods, and gene cloning techniques resulted in a pure product of a defined primary structure, which can be obtained in virtually unlimited quantities for further probing its structure and function. The fact that the symposium on Growth and Differentiation Factors in this conference did not include a single presentation on IL2 is a testimony to the rapid progress in this area." @default.
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- W4627269 date "1985-01-01" @default.
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- W4627269 title "Regulation of T Cell Growth" @default.
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- W4627269 doi "https://doi.org/10.1007/978-1-4612-4996-2_36" @default.
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