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- W46691054 abstract "In Chapter 5, this volume, Villegas described several decades of research on squid giant axons that has revealed an elaborate signaling cascade between neurons and glia mediated by transmitter agents secreted by both cell types. Comparable studies of giant nerve fibers in the central nervous system (CNS) of crayfish have confirmed the generality of those findings, at least in invertebrates (Lieberman et al., 1994). Since these intercellular interactions alter the ion permeability of the adaxonal glial cells, they can influence the ion composition of the periaxonal space and thereby the efficiency of electrical signal generation and propagation in the axon. Because of the important implications of this effect for function of the nervous system, we have attempted to identify the chemical mediator that is released by the active axon and the mechanisms by which its availability and release are regulated." @default.
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- W46691054 date "1995-01-01" @default.
- W46691054 modified "2023-09-27" @default.
- W46691054 title "Glutamate-Mediated Neuron—Glia Signaling in Invertebrates and Vertebrates" @default.
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- W46691054 doi "https://doi.org/10.1007/978-1-59259-468-9_6" @default.
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