Matches in SemOpenAlex for { <https://semopenalex.org/work/W46694385> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W46694385 endingPage "24" @default.
- W46694385 startingPage "19" @default.
- W46694385 abstract "Within the last decade, two different inborn enzyme abnormalities were identified as causing excessive purine production in man: deficiency of hypoxanthine-guanine phosphoribosyltransferase(HGPRT) whether partial (1) or complete (2), and superactivity of 5-phospho-ribosyl-1-pyrophosphate (PRPP)synthetase, due to feedback-resistance (3–5) or various other molecular alterations. The finding of excessive de novo purine nucleotide synthesis in these enzyme abnormalities has contributed markedly to the understanding of the normal metabolism of purines in man, mainly in revealing the importance of HGPRT activity and of PRPP availability in the regulation of de novo purine synthesis.KeywordsGuanine NucleotidePurine MetabolismNucleotide SynthesisPurine SynthesisPurine DerivativeThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W46694385 created "2016-06-24" @default.
- W46694385 creator A5069750041 @default.
- W46694385 creator A5080723862 @default.
- W46694385 date "1980-01-01" @default.
- W46694385 modified "2023-09-27" @default.
- W46694385 title "Alterations in Purine Metabolism in Cultured Fibroblasts with HGPRT Deficiency and with PRPP Synthetase Superactivity" @default.
- W46694385 cites W1964895426 @default.
- W46694385 cites W2013157260 @default.
- W46694385 cites W2083656967 @default.
- W46694385 cites W2120613619 @default.
- W46694385 doi "https://doi.org/10.1007/978-1-4684-8559-2_4" @default.
- W46694385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/232629" @default.
- W46694385 hasPublicationYear "1980" @default.
- W46694385 type Work @default.
- W46694385 sameAs 46694385 @default.
- W46694385 citedByCount "1" @default.
- W46694385 crossrefType "book-chapter" @default.
- W46694385 hasAuthorship W46694385A5069750041 @default.
- W46694385 hasAuthorship W46694385A5080723862 @default.
- W46694385 hasConcept C104317684 @default.
- W46694385 hasConcept C143065580 @default.
- W46694385 hasConcept C169586020 @default.
- W46694385 hasConcept C181199279 @default.
- W46694385 hasConcept C185592680 @default.
- W46694385 hasConcept C194101687 @default.
- W46694385 hasConcept C2776476023 @default.
- W46694385 hasConcept C2777766392 @default.
- W46694385 hasConcept C2777991568 @default.
- W46694385 hasConcept C2781116151 @default.
- W46694385 hasConcept C40507961 @default.
- W46694385 hasConcept C512185932 @default.
- W46694385 hasConcept C55493867 @default.
- W46694385 hasConcept C62231903 @default.
- W46694385 hasConcept C78179603 @default.
- W46694385 hasConcept C86803240 @default.
- W46694385 hasConcept C88742014 @default.
- W46694385 hasConceptScore W46694385C104317684 @default.
- W46694385 hasConceptScore W46694385C143065580 @default.
- W46694385 hasConceptScore W46694385C169586020 @default.
- W46694385 hasConceptScore W46694385C181199279 @default.
- W46694385 hasConceptScore W46694385C185592680 @default.
- W46694385 hasConceptScore W46694385C194101687 @default.
- W46694385 hasConceptScore W46694385C2776476023 @default.
- W46694385 hasConceptScore W46694385C2777766392 @default.
- W46694385 hasConceptScore W46694385C2777991568 @default.
- W46694385 hasConceptScore W46694385C2781116151 @default.
- W46694385 hasConceptScore W46694385C40507961 @default.
- W46694385 hasConceptScore W46694385C512185932 @default.
- W46694385 hasConceptScore W46694385C55493867 @default.
- W46694385 hasConceptScore W46694385C62231903 @default.
- W46694385 hasConceptScore W46694385C78179603 @default.
- W46694385 hasConceptScore W46694385C86803240 @default.
- W46694385 hasConceptScore W46694385C88742014 @default.
- W46694385 hasLocation W466943851 @default.
- W46694385 hasLocation W466943852 @default.
- W46694385 hasOpenAccess W46694385 @default.
- W46694385 hasPrimaryLocation W466943851 @default.
- W46694385 hasRelatedWork W12529343 @default.
- W46694385 hasRelatedWork W1536543092 @default.
- W46694385 hasRelatedWork W1580777482 @default.
- W46694385 hasRelatedWork W1979829451 @default.
- W46694385 hasRelatedWork W2013157260 @default.
- W46694385 hasRelatedWork W2073782571 @default.
- W46694385 hasRelatedWork W2093139670 @default.
- W46694385 hasRelatedWork W2106971666 @default.
- W46694385 hasRelatedWork W2409635355 @default.
- W46694385 hasRelatedWork W46694385 @default.
- W46694385 isParatext "false" @default.
- W46694385 isRetracted "false" @default.
- W46694385 magId "46694385" @default.
- W46694385 workType "book-chapter" @default.