Matches in SemOpenAlex for { <https://semopenalex.org/work/W4685065> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4685065 endingPage "61" @default.
- W4685065 startingPage "59" @default.
- W4685065 abstract "Androgen insensitivity syndrome (AIS) is a rare X-linked disorder in which 46,XY subjects have complete (CAIS) or partial (PAIS) impairment of androgen action due to abnormalities of the androgen receptor (AR). We studied 25 Brazilian subjects with AIS confirmed by identification of mutations in the AR and concluded that (1) identification of mutations in the AR is essential to classify patients with 46,XY DSD as PAIS; (2) family history and gynecomastia were useful to select patients for genetic studies; (3) gynecomastia developed in CAIS due to unopposed effect of normal estrogen levels; (4) absence of axillary hair was a better indicator of CAIS than absence of pubic hair; (5) serum LH and LH × T product were elevated in all pubertal patients, while testosterone was normal or elevated and serum FSH normal in most patients; (6) phallic size and its response to high-dose testosterone therapy were usually subnormal, but variable in PAIS; (7) in patients with female social sex, vaginal dilation was useful to obtain an adequate length for sexual intercourse; (8) all PAIS raised as girls as well as those raised as boys maintained gender assigned before puberty, despite overlap in phallic size at puberty; (9) adult height was intermediate between normal males and females; and (10) low spine BMD before gonadectomy and even in estrogen-compliant CAIS may reflect androgen resistance at the bone level." @default.
- W4685065 created "2016-06-24" @default.
- W4685065 creator A5006947072 @default.
- W4685065 creator A5029771504 @default.
- W4685065 creator A5048394640 @default.
- W4685065 creator A5051651703 @default.
- W4685065 creator A5068669849 @default.
- W4685065 creator A5070035952 @default.
- W4685065 creator A5071033918 @default.
- W4685065 date "2011-01-01" @default.
- W4685065 modified "2023-10-16" @default.
- W4685065 title "46,XY Disorders of Sex Development (46,XY DSD) due to Androgen Receptor Defects: Androgen Insensitivity Syndrome" @default.
- W4685065 cites W1965845237 @default.
- W4685065 cites W1968070511 @default.
- W4685065 cites W2011689173 @default.
- W4685065 doi "https://doi.org/10.1007/978-1-4419-8002-1_14" @default.
- W4685065 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21691956" @default.
- W4685065 hasPublicationYear "2011" @default.
- W4685065 type Work @default.
- W4685065 sameAs 4685065 @default.
- W4685065 citedByCount "13" @default.
- W4685065 countsByYear W46850652012 @default.
- W4685065 countsByYear W46850652013 @default.
- W4685065 countsByYear W46850652014 @default.
- W4685065 countsByYear W46850652016 @default.
- W4685065 countsByYear W46850652017 @default.
- W4685065 countsByYear W46850652018 @default.
- W4685065 countsByYear W46850652019 @default.
- W4685065 countsByYear W46850652021 @default.
- W4685065 countsByYear W46850652022 @default.
- W4685065 countsByYear W46850652023 @default.
- W4685065 crossrefType "book-chapter" @default.
- W4685065 hasAuthorship W4685065A5006947072 @default.
- W4685065 hasAuthorship W4685065A5029771504 @default.
- W4685065 hasAuthorship W4685065A5048394640 @default.
- W4685065 hasAuthorship W4685065A5051651703 @default.
- W4685065 hasAuthorship W4685065A5068669849 @default.
- W4685065 hasAuthorship W4685065A5070035952 @default.
- W4685065 hasAuthorship W4685065A5071033918 @default.
- W4685065 hasConcept C121608353 @default.
- W4685065 hasConcept C126322002 @default.
- W4685065 hasConcept C134018914 @default.
- W4685065 hasConcept C2777164284 @default.
- W4685065 hasConcept C2777252872 @default.
- W4685065 hasConcept C2777691561 @default.
- W4685065 hasConcept C2777911890 @default.
- W4685065 hasConcept C2778952551 @default.
- W4685065 hasConcept C2779279991 @default.
- W4685065 hasConcept C2780192828 @default.
- W4685065 hasConcept C2781037291 @default.
- W4685065 hasConcept C61367390 @default.
- W4685065 hasConcept C71315377 @default.
- W4685065 hasConcept C71924100 @default.
- W4685065 hasConceptScore W4685065C121608353 @default.
- W4685065 hasConceptScore W4685065C126322002 @default.
- W4685065 hasConceptScore W4685065C134018914 @default.
- W4685065 hasConceptScore W4685065C2777164284 @default.
- W4685065 hasConceptScore W4685065C2777252872 @default.
- W4685065 hasConceptScore W4685065C2777691561 @default.
- W4685065 hasConceptScore W4685065C2777911890 @default.
- W4685065 hasConceptScore W4685065C2778952551 @default.
- W4685065 hasConceptScore W4685065C2779279991 @default.
- W4685065 hasConceptScore W4685065C2780192828 @default.
- W4685065 hasConceptScore W4685065C2781037291 @default.
- W4685065 hasConceptScore W4685065C61367390 @default.
- W4685065 hasConceptScore W4685065C71315377 @default.
- W4685065 hasConceptScore W4685065C71924100 @default.
- W4685065 hasLocation W46850651 @default.
- W4685065 hasLocation W46850652 @default.
- W4685065 hasOpenAccess W4685065 @default.
- W4685065 hasPrimaryLocation W46850651 @default.
- W4685065 hasRelatedWork W1596407667 @default.
- W4685065 hasRelatedWork W1981433740 @default.
- W4685065 hasRelatedWork W1986311037 @default.
- W4685065 hasRelatedWork W2000206763 @default.
- W4685065 hasRelatedWork W2004261902 @default.
- W4685065 hasRelatedWork W2023640123 @default.
- W4685065 hasRelatedWork W2112219216 @default.
- W4685065 hasRelatedWork W2469917194 @default.
- W4685065 hasRelatedWork W3029399796 @default.
- W4685065 hasRelatedWork W3145783760 @default.
- W4685065 isParatext "false" @default.
- W4685065 isRetracted "false" @default.
- W4685065 magId "4685065" @default.
- W4685065 workType "book-chapter" @default.