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- W47346417 abstract "Immune thrombocytopenic purpura (ITP) is a condition with potential hazard during pregnancy for both mother and fetus if platelet concentrations fall below a critical level. This report describes the use of laparoscopic splenectomy following unsuccessful medical management.A 35-year-old primigravid woman with systemic lupus erythematosis (SLE) developed ITP several years before becoming pregnant. She was treated early in pregnancy with high-dose oral prednisone and weekly intravenous immunoglobulin (IVIG) alternating with anti-D immune globulin, but laparoscopic splenectomy was indicated at 20 weeks' gestation because of thrombocytopenia. Following surgery, she continued prednisone and intermittent IVIG therapy until spontaneous delivery at 34 weeks' gestation. A small accessory spleen was identified postpartum by nuclear medicine scan. Satisfactory platelet concentrations were maintained postpartum using danazol and prednisone.Laparoscopic splenectomy is a therapeutic option for women with ITP during pregnancy that fails to respond to medical management." @default.
- W47346417 created "2016-06-24" @default.
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- W47346417 date "2005-08-01" @default.
- W47346417 modified "2023-09-30" @default.
- W47346417 title "Laparoscopic Splenectomy for the Treatment of Refractory Immune Thrombocytopenia in Pregnancy" @default.
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- W47346417 doi "https://doi.org/10.1016/s1701-2163(16)30729-0" @default.
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