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- W47363074 abstract "Cell surface associated mucins are a class of transmembrane glycoproteins that protrude high above the cell surface and can mask other cell surface molecules, thereby interfering with the function of the latter molecules. In particular, adhesion molecules are affected, which has important consequences for cellular processes that are dependent on adhesion such as cytolysis by immune cells and probably also invasion and metastasis. Episialin is such a cell-associated mucin which is highly overexpressed on certain carcinomas and it can serve as a prototypic cell associated mucin. Here, we discuss its structure, its effect on cellular adhesionin vitro andin vivo and the consequences for LAK cell and CTL mediated cytolysis. In addition, we discuss the biological impact of other related molecules." @default.
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- W47363074 date "1995-01-01" @default.
- W47363074 modified "2023-10-03" @default.
- W47363074 title "Cell surface associated mucins: Structure and effects on cell adhesion" @default.
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- W47363074 doi "https://doi.org/10.1007/978-3-0348-9057-1_18" @default.
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