Matches in SemOpenAlex for { <https://semopenalex.org/work/W47422851> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W47422851 endingPage "594" @default.
- W47422851 startingPage "589" @default.
- W47422851 abstract "1. In systemic hypertension the pulmonary vessels show an excessive tone at rest and hyper-react to adrenoceptor stimulation. Alterations in Ca2+ handling by the vascular smooth muscle cells seem to underlie these disorders. Alveolar hypoxia also constricts pulmonary arteries, increasing the intracellular Ca2+ availability for smooth muscle contraction. This suggests the hypothesis that hypoxic pulmonary vasoconstriction depends on similar biochemical disorders, and that the response to the hypoxic stimulus may be emphasized in high blood pressure. 2. In 21 hypertensive and 10 normotensive men, pulmonary arterial pressure and arteriolar resistance have been evaluated during air respiration and after 15 min of breathing 17, 15 and 12% oxygen in nitrogen. Curves relating changes in pulmonary arterial pressure and arteriolar resistance to the oxygen content of inspired gas had a similar configuration in the two populations, but in hypertension were steeper and significantly shifted to the left of those in normotension, reflecting a lower threshold and an enhanced vasoconstrictor reactivity. 3. This pattern was not related to differences in severity of the hypoxic stimulus, degree of hypocapnia and respiratory alkalosis induced by hypoxia, and plasma catecholamines. 4. The association of high blood pressure with enhanced pulmonary vasoreactivity to alveolar hypoxia could have clinical implications in patients who are chronically hypoxic and have systemic hypertension." @default.
- W47422851 created "2016-06-24" @default.
- W47422851 creator A5013057215 @default.
- W47422851 creator A5030597244 @default.
- W47422851 creator A5036779314 @default.
- W47422851 creator A5038767012 @default.
- W47422851 creator A5042864961 @default.
- W47422851 creator A5052759984 @default.
- W47422851 creator A5060444784 @default.
- W47422851 date "1989-06-01" @default.
- W47422851 modified "2023-09-27" @default.
- W47422851 title "Enhancement of the pulmonary vasoconstriction reaction to alveolar hypoxia in systemic high blood pressure" @default.
- W47422851 doi "https://doi.org/10.1042/cs0760589" @default.
- W47422851 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2736878" @default.
- W47422851 hasPublicationYear "1989" @default.
- W47422851 type Work @default.
- W47422851 sameAs 47422851 @default.
- W47422851 citedByCount "8" @default.
- W47422851 countsByYear W474228512014 @default.
- W47422851 countsByYear W474228512016 @default.
- W47422851 crossrefType "journal-article" @default.
- W47422851 hasAuthorship W47422851A5013057215 @default.
- W47422851 hasAuthorship W47422851A5030597244 @default.
- W47422851 hasAuthorship W47422851A5036779314 @default.
- W47422851 hasAuthorship W47422851A5038767012 @default.
- W47422851 hasAuthorship W47422851A5042864961 @default.
- W47422851 hasAuthorship W47422851A5052759984 @default.
- W47422851 hasAuthorship W47422851A5060444784 @default.
- W47422851 hasConcept C126322002 @default.
- W47422851 hasConcept C164705383 @default.
- W47422851 hasConcept C178790620 @default.
- W47422851 hasConcept C185592680 @default.
- W47422851 hasConcept C2777037550 @default.
- W47422851 hasConcept C2778866228 @default.
- W47422851 hasConcept C2779961880 @default.
- W47422851 hasConcept C2780930700 @default.
- W47422851 hasConcept C2780940725 @default.
- W47422851 hasConcept C29323129 @default.
- W47422851 hasConcept C42219234 @default.
- W47422851 hasConcept C534529494 @default.
- W47422851 hasConcept C540031477 @default.
- W47422851 hasConcept C58245268 @default.
- W47422851 hasConcept C71924100 @default.
- W47422851 hasConcept C7836513 @default.
- W47422851 hasConcept C84393581 @default.
- W47422851 hasConceptScore W47422851C126322002 @default.
- W47422851 hasConceptScore W47422851C164705383 @default.
- W47422851 hasConceptScore W47422851C178790620 @default.
- W47422851 hasConceptScore W47422851C185592680 @default.
- W47422851 hasConceptScore W47422851C2777037550 @default.
- W47422851 hasConceptScore W47422851C2778866228 @default.
- W47422851 hasConceptScore W47422851C2779961880 @default.
- W47422851 hasConceptScore W47422851C2780930700 @default.
- W47422851 hasConceptScore W47422851C2780940725 @default.
- W47422851 hasConceptScore W47422851C29323129 @default.
- W47422851 hasConceptScore W47422851C42219234 @default.
- W47422851 hasConceptScore W47422851C534529494 @default.
- W47422851 hasConceptScore W47422851C540031477 @default.
- W47422851 hasConceptScore W47422851C58245268 @default.
- W47422851 hasConceptScore W47422851C71924100 @default.
- W47422851 hasConceptScore W47422851C7836513 @default.
- W47422851 hasConceptScore W47422851C84393581 @default.
- W47422851 hasIssue "6" @default.
- W47422851 hasLocation W474228511 @default.
- W47422851 hasLocation W474228512 @default.
- W47422851 hasOpenAccess W47422851 @default.
- W47422851 hasPrimaryLocation W474228511 @default.
- W47422851 hasRelatedWork W1518999864 @default.
- W47422851 hasRelatedWork W1880961408 @default.
- W47422851 hasRelatedWork W1981678238 @default.
- W47422851 hasRelatedWork W2030660333 @default.
- W47422851 hasRelatedWork W2117612990 @default.
- W47422851 hasRelatedWork W2319686527 @default.
- W47422851 hasRelatedWork W2463110717 @default.
- W47422851 hasRelatedWork W301035058 @default.
- W47422851 hasRelatedWork W335837758 @default.
- W47422851 hasRelatedWork W47422851 @default.
- W47422851 hasVolume "76" @default.
- W47422851 isParatext "false" @default.
- W47422851 isRetracted "false" @default.
- W47422851 magId "47422851" @default.
- W47422851 workType "article" @default.