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- W47593844 abstract "Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its a-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders.This is a randomized, crossover, open-labeled, two- center study. Forty patients (20 open-angle glaucoma patients and 20 healthy subjects) were treated with ibopamine 2% eye drops and phenylephrine 10% eye drops.Ibopamine induced a significant increase in IOP only in glaucomatous eyes (p<0.001) without a significant hypertensive effect in normal eyes. Ibopamine and phenylephrine showed a similar mydriatic activity but ibopamine was able to induce an hypertensive effect only in glaucomatous eyes.The results confirm the use of ibopamine as provocative test in detection of hydrodynamic disorders.(Eur J Ophthalmol 2004; 14: #-13)." @default.
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- W47593844 date "2004-11-01" @default.
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- W47593844 title "The effects of 2% ibopamine eye drops on the intraocular pressure and pupil motility of patients with open-angle glaucoma." @default.
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- W47593844 doi "https://doi.org/10.5301/ejo.2008.5386" @default.
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