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- W47626416 abstract "As documented elsewhere in this book, heat shock proteins (HSPs) clearly play a central role in activation and modulation of unspecific as well as specific immune responses. In this chapter, we will describe early atherosclerosis as an autoimmune disorder and heat shock protein 60 (HSP60) as the culprit-autoantigen. After a brief review of experimental in vitro data and results from animal experiments, we will focus on clinical data confirming our pathophysiological concept that early atherosclerosis is the price we pay for protective immunity against microbial HSP60 or bona fide autoimmunity to eliminate biochemically-altered autologous HSP60.KeywordsHeat Shock ProteinEarly AtherosclerosisAtherosclerosis Risk FactorHuman HSP60High Resolution UltrasoundThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W47626416 created "2016-06-24" @default.
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- W47626416 date "2003-01-01" @default.
- W47626416 modified "2023-10-16" @default.
- W47626416 title "Immunity to heat shock proteins and atherosclerosis" @default.
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- W47626416 doi "https://doi.org/10.1007/978-3-0348-8028-2_11" @default.
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