FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W47879935> ?p ?o ?g. }

• W47879935 abstract "More than a decade ago, Michell (1975) noted that receptors that mediate the release of calcium also activate inositol lipid turnover, and suggested that these two events might be related. Since then, enormous strides have been made in the elucidation of the biochemical mechanism and the physiological role of agonist-induced inositol lipid turnover. Many extensive reviews of this subject have appeared recently (e.g., Abdel-Latif, 1986; Berridge, 1986; Exton, 1986; Nahorski et al., 1986), and the current review will only briefly summarize the highlights of this signaling mechanism. The key reaction is the hydrolysis of plasma membrane phosphoinositides by a phosphodiesterase, phospholipase C, to yield second messengers (Fig. 1). Three phosphoinositides, phosphatidylinositol (PI), phosphatidylinositol-4-monophosphate (PIP), and phosphatidylinostiol-4,5-bisphosphate (PIP2), are degraded by phospholipase C to form diacylglycerol (DAG) and inositol phosphates. It is generally thought that the primary substrate for receptor-activated phospholipase C is PIP2, with hydrolysis yielding two second messengers, DAG and inositol-1,4,5-trisphosphate (IP3). Evidence exists that, in some systems, PI and PIP are also hydrolyzed by receptor-activated phospholipase C." @default.
• W47879935 created "2016-06-24" @default.
• W47879935 creator A5087737932 @default.
• W47879935 date "1988-01-01" @default.
• W47879935 modified "2023-09-29" @default.
• W47879935 title "5-HT Receptors Coupled to Phosphoinositide Hydrolysis" @default.
• W47879935 cites W1583566865 @default.
• W47879935 cites W1676833966 @default.
• W47879935 cites W17828523 @default.
• W47879935 cites W186192584 @default.
• W47879935 cites W1889236699 @default.
• W47879935 cites W1970696947 @default.
• W47879935 cites W1978040735 @default.
• W47879935 cites W1979180190 @default.
• W47879935 cites W1984029095 @default.
• W47879935 cites W1986919672 @default.
• W47879935 cites W2006308555 @default.
• W47879935 cites W2009914768 @default.
• W47879935 cites W2015242960 @default.
• W47879935 cites W2025948426 @default.
• W47879935 cites W2026507453 @default.
• W47879935 cites W2028510491 @default.
• W47879935 cites W2030162571 @default.
• W47879935 cites W2032153694 @default.
• W47879935 cites W2048225040 @default.
• W47879935 cites W2050171079 @default.
• W47879935 cites W2062884452 @default.
• W47879935 cites W2063085120 @default.
• W47879935 cites W2077902136 @default.
• W47879935 cites W2079264295 @default.
• W47879935 cites W2090708109 @default.
• W47879935 cites W2090839129 @default.
• W47879935 cites W2092208612 @default.
• W47879935 cites W2093336211 @default.
• W47879935 cites W2098261393 @default.
• W47879935 cites W2122914581 @default.
• W47879935 cites W2138765408 @default.
• W47879935 cites W2148495511 @default.
• W47879935 cites W2154588586 @default.
• W47879935 cites W2165670570 @default.
• W47879935 cites W2238525991 @default.
• W47879935 cites W2367567488 @default.
• W47879935 cites W2411609888 @default.
• W47879935 cites W4252044985 @default.
• W47879935 doi "https://doi.org/10.1007/978-1-4612-4560-5_6" @default.
• W47879935 hasPublicationYear "1988" @default.
• W47879935 type Work @default.
• W47879935 sameAs 47879935 @default.
• W47879935 citedByCount "14" @default.
• W47879935 crossrefType "book-chapter" @default.
• W47879935 hasAuthorship W47879935A5087737932 @default.
• W47879935 hasConcept C12927208 @default.
• W47879935 hasConcept C152624196 @default.
• W47879935 hasConcept C163235415 @default.
• W47879935 hasConcept C170493617 @default.
• W47879935 hasConcept C181199279 @default.
• W47879935 hasConcept C185592680 @default.
• W47879935 hasConcept C195794163 @default.
• W47879935 hasConcept C2777427919 @default.
• W47879935 hasConcept C2778597717 @default.
• W47879935 hasConcept C2778618036 @default.
• W47879935 hasConcept C2780610907 @default.
• W47879935 hasConcept C2781387506 @default.
• W47879935 hasConcept C36020004 @default.
• W47879935 hasConcept C55493867 @default.
• W47879935 hasConcept C62478195 @default.
• W47879935 hasConcept C62826618 @default.
• W47879935 hasConcept C66135807 @default.
• W47879935 hasConcept C78297661 @default.
• W47879935 hasConcept C80631254 @default.
• W47879935 hasConcept C86803240 @default.
• W47879935 hasConcept C95444343 @default.
• W47879935 hasConceptScore W47879935C12927208 @default.
• W47879935 hasConceptScore W47879935C152624196 @default.
• W47879935 hasConceptScore W47879935C163235415 @default.
• W47879935 hasConceptScore W47879935C170493617 @default.
• W47879935 hasConceptScore W47879935C181199279 @default.
• W47879935 hasConceptScore W47879935C185592680 @default.
• W47879935 hasConceptScore W47879935C195794163 @default.
• W47879935 hasConceptScore W47879935C2777427919 @default.
• W47879935 hasConceptScore W47879935C2778597717 @default.
• W47879935 hasConceptScore W47879935C2778618036 @default.
• W47879935 hasConceptScore W47879935C2780610907 @default.
• W47879935 hasConceptScore W47879935C2781387506 @default.
• W47879935 hasConceptScore W47879935C36020004 @default.
• W47879935 hasConceptScore W47879935C55493867 @default.
• W47879935 hasConceptScore W47879935C62478195 @default.
• W47879935 hasConceptScore W47879935C62826618 @default.
• W47879935 hasConceptScore W47879935C66135807 @default.
• W47879935 hasConceptScore W47879935C78297661 @default.
• W47879935 hasConceptScore W47879935C80631254 @default.
• W47879935 hasConceptScore W47879935C86803240 @default.
• W47879935 hasConceptScore W47879935C95444343 @default.
• W47879935 hasLocation W478799351 @default.
• W47879935 hasOpenAccess W47879935 @default.
• W47879935 hasPrimaryLocation W478799351 @default.
• W47879935 hasRelatedWork W10072003 @default.
• W47879935 hasRelatedWork W12180132 @default.
• W47879935 hasRelatedWork W1486430016 @default.
• W47879935 hasRelatedWork W1804473676 @default.

• next