Matches in SemOpenAlex for { <https://semopenalex.org/work/W48161818> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W48161818 endingPage "788" @default.
- W48161818 startingPage "784" @default.
- W48161818 abstract "To define the epidemiology, pathogenesis, pathology, presentation, and management of tuberculous mycotic aneurysm of the aorta (TBAA) in the therapeutic era, we reviewed all of the cases reported in the English language literature from 1945 to the present. To the 39 cases in the published literature, we add two cases of our own. Although it is exceedingly rare, the prevalence of this lesion has remained relatively constant. In 75% of the cases, TBAA appeared to result from erosion of the aortic wall by a contiguous focus; 25% from direct seeding of the aortic intima or of the adventitia or media (via the vasa vasorum). Most of the aneurysms were saccular (90%) and false (88%). The thoracic and abdominal aortas were affected with equal frequency. The mean (± SD) age of the patients was 50 ± 16 years. Twenty-two were men, and 19 were women. In 63% of the cases, tuberculosis (TB) was diagnosed at presentation. Disseminated TB was present in 46% of the cases. One or more of three clinical scenarios suggested TBAA: persistent pain, major bleeding, and a palpable or radiographically visible para-aortic mass, especially if it is expanding or pulsatile. In turn, each of these findings suggested a complication of TBAA that may be an indication for surgical intervention. Among the patients who were offered both medical and surgical treatment, 20 of 23 (87%) survived. Among those who were offered only one form of treatment or were offered no treatment at all there were no survivors. Both in situ reconstruction with a prosthetic graft, and extra-anatomic bypass appeared to offer excellent results, provided that an effective regimen of antituberculous drugs was delivered postoperatively. We offer our conclusions: (1) symptomatic TBAA is a rare but uniformly fatal lesion if not diagnosed promptly, (2) in the context of active TB, and especially miliary TB, TBAA should be suspected whenever one or more of the three clinical scenarios are present, and (3) combined medical and surgical therapy appears to offer the best chance of a cure." @default.
- W48161818 created "2016-06-24" @default.
- W48161818 creator A5017567369 @default.
- W48161818 creator A5089635476 @default.
- W48161818 date "1950-11-01" @default.
- W48161818 modified "2023-10-18" @default.
- W48161818 title "Nontraumatic aortic perforations into gastrointestinal tract" @default.
- W48161818 cites W1537989243 @default.
- W48161818 cites W1565114400 @default.
- W48161818 cites W1601642266 @default.
- W48161818 cites W2030793975 @default.
- W48161818 cites W2036354307 @default.
- W48161818 cites W2088810538 @default.
- W48161818 cites W2092402278 @default.
- W48161818 cites W2132128476 @default.
- W48161818 cites W2319550190 @default.
- W48161818 cites W2322684371 @default.
- W48161818 doi "https://doi.org/10.1016/0002-8703(50)90208-0" @default.
- W48161818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14783073" @default.
- W48161818 hasPublicationYear "1950" @default.
- W48161818 type Work @default.
- W48161818 sameAs 48161818 @default.
- W48161818 citedByCount "21" @default.
- W48161818 countsByYear W481618182016 @default.
- W48161818 crossrefType "journal-article" @default.
- W48161818 hasAuthorship W48161818A5017567369 @default.
- W48161818 hasAuthorship W48161818A5089635476 @default.
- W48161818 hasConcept C107130276 @default.
- W48161818 hasConcept C126322002 @default.
- W48161818 hasConcept C126838900 @default.
- W48161818 hasConcept C141071460 @default.
- W48161818 hasConcept C142724271 @default.
- W48161818 hasConcept C2776178081 @default.
- W48161818 hasConcept C2776716733 @default.
- W48161818 hasConcept C2777323849 @default.
- W48161818 hasConcept C2777601897 @default.
- W48161818 hasConcept C2777714996 @default.
- W48161818 hasConcept C2777818683 @default.
- W48161818 hasConcept C2779205420 @default.
- W48161818 hasConcept C2779980429 @default.
- W48161818 hasConcept C2780314925 @default.
- W48161818 hasConcept C2780520971 @default.
- W48161818 hasConcept C2781069245 @default.
- W48161818 hasConcept C2781156865 @default.
- W48161818 hasConcept C71924100 @default.
- W48161818 hasConcept C79191276 @default.
- W48161818 hasConcept C81182388 @default.
- W48161818 hasConceptScore W48161818C107130276 @default.
- W48161818 hasConceptScore W48161818C126322002 @default.
- W48161818 hasConceptScore W48161818C126838900 @default.
- W48161818 hasConceptScore W48161818C141071460 @default.
- W48161818 hasConceptScore W48161818C142724271 @default.
- W48161818 hasConceptScore W48161818C2776178081 @default.
- W48161818 hasConceptScore W48161818C2776716733 @default.
- W48161818 hasConceptScore W48161818C2777323849 @default.
- W48161818 hasConceptScore W48161818C2777601897 @default.
- W48161818 hasConceptScore W48161818C2777714996 @default.
- W48161818 hasConceptScore W48161818C2777818683 @default.
- W48161818 hasConceptScore W48161818C2779205420 @default.
- W48161818 hasConceptScore W48161818C2779980429 @default.
- W48161818 hasConceptScore W48161818C2780314925 @default.
- W48161818 hasConceptScore W48161818C2780520971 @default.
- W48161818 hasConceptScore W48161818C2781069245 @default.
- W48161818 hasConceptScore W48161818C2781156865 @default.
- W48161818 hasConceptScore W48161818C71924100 @default.
- W48161818 hasConceptScore W48161818C79191276 @default.
- W48161818 hasConceptScore W48161818C81182388 @default.
- W48161818 hasIssue "5" @default.
- W48161818 hasLocation W481618181 @default.
- W48161818 hasLocation W481618182 @default.
- W48161818 hasOpenAccess W48161818 @default.
- W48161818 hasPrimaryLocation W481618181 @default.
- W48161818 hasRelatedWork W1987607697 @default.
- W48161818 hasRelatedWork W2003196651 @default.
- W48161818 hasRelatedWork W2020819292 @default.
- W48161818 hasRelatedWork W2023425063 @default.
- W48161818 hasRelatedWork W2024390970 @default.
- W48161818 hasRelatedWork W2172109404 @default.
- W48161818 hasRelatedWork W2264826090 @default.
- W48161818 hasRelatedWork W2784563960 @default.
- W48161818 hasRelatedWork W3141061118 @default.
- W48161818 hasRelatedWork W1972471897 @default.
- W48161818 hasVolume "40" @default.
- W48161818 isParatext "false" @default.
- W48161818 isRetracted "false" @default.
- W48161818 magId "48161818" @default.
- W48161818 workType "article" @default.