Matches in SemOpenAlex for { <https://semopenalex.org/work/W48307279> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W48307279 endingPage "82" @default.
- W48307279 startingPage "74" @default.
- W48307279 abstract "Measurement of cardiac markers in blood has been the mainstay for diagnosis of acute myocardial infarction for nearly 50 years. The field has evolved from measurement of enzyme activity to mass concentrations of proteins using automated non-isotopic immunoassays. With changing clinical practices, cardiac markers are now needed to detect the presence of minor myocardial infarction in patients with unstable angina. Outcome studies have shown that patients with increased troponin are at high short-term risk for death and AMI. Recent developments involve the use of cardiac markers to select the most appropriate therapy for patients with acute coronary syndromes. The success of new cardiac markers such as troponin is due to their high cardiac specificity and the existence of assays with low detection limits. Traditional enzymes such as CK and CK-MB are thought to be released only in situations of irreversible myocardial necrosis. In the case of cardiac troponin, clinical observations and animal studies suggest that cytosolic free troponin may be released in reversible ischemia in addition to irreversible cell damage. The IFCC S-SCM has recommended use of two cut-off concentrations for cardiac troponin to differentiate normal from minor myocardial injury and AMI. A low cut-off may detect reversible ischemic events in some cases." @default.
- W48307279 created "2016-06-24" @default.
- W48307279 creator A5079517489 @default.
- W48307279 date "1999-01-01" @default.
- W48307279 modified "2023-10-16" @default.
- W48307279 title "Biochemical markers of cardiac damage: from traditional enzymes to cardiac-specific proteins. IFCC Subcommittee on Standardization of Cardiac Markers (S-SCM)." @default.
- W48307279 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10389205" @default.
- W48307279 hasPublicationYear "1999" @default.
- W48307279 type Work @default.
- W48307279 sameAs 48307279 @default.
- W48307279 citedByCount "7" @default.
- W48307279 countsByYear W483072792016 @default.
- W48307279 countsByYear W483072792020 @default.
- W48307279 crossrefType "journal-article" @default.
- W48307279 hasAuthorship W48307279A5079517489 @default.
- W48307279 hasConcept C115725540 @default.
- W48307279 hasConcept C126322002 @default.
- W48307279 hasConcept C164705383 @default.
- W48307279 hasConcept C2777785093 @default.
- W48307279 hasConcept C2778425758 @default.
- W48307279 hasConcept C2778532138 @default.
- W48307279 hasConcept C2910551752 @default.
- W48307279 hasConcept C36036425 @default.
- W48307279 hasConcept C500558357 @default.
- W48307279 hasConcept C71924100 @default.
- W48307279 hasConceptScore W48307279C115725540 @default.
- W48307279 hasConceptScore W48307279C126322002 @default.
- W48307279 hasConceptScore W48307279C164705383 @default.
- W48307279 hasConceptScore W48307279C2777785093 @default.
- W48307279 hasConceptScore W48307279C2778425758 @default.
- W48307279 hasConceptScore W48307279C2778532138 @default.
- W48307279 hasConceptScore W48307279C2910551752 @default.
- W48307279 hasConceptScore W48307279C36036425 @default.
- W48307279 hasConceptScore W48307279C500558357 @default.
- W48307279 hasConceptScore W48307279C71924100 @default.
- W48307279 hasLocation W483072791 @default.
- W48307279 hasOpenAccess W48307279 @default.
- W48307279 hasPrimaryLocation W483072791 @default.
- W48307279 hasRelatedWork W2000119112 @default.
- W48307279 hasRelatedWork W2036847054 @default.
- W48307279 hasRelatedWork W2115768769 @default.
- W48307279 hasRelatedWork W2144444505 @default.
- W48307279 hasRelatedWork W2380680968 @default.
- W48307279 hasRelatedWork W2387642730 @default.
- W48307279 hasRelatedWork W2422710323 @default.
- W48307279 hasRelatedWork W2463286766 @default.
- W48307279 hasRelatedWork W29490996 @default.
- W48307279 hasRelatedWork W48307279 @default.
- W48307279 hasVolume "230" @default.
- W48307279 isParatext "false" @default.
- W48307279 isRetracted "false" @default.
- W48307279 magId "48307279" @default.
- W48307279 workType "article" @default.