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• W48591159 abstract "High prolactin hormone level in the blood is known as hyperprolactinemia. The most common symptom of hyperprolactinemia is galactorrhea, in which spontaneous milky discharge is seen from all ducts of the two mammary glands. Dopamine has an inhibitor effect on prolactin, in the tuberoinfundibular tract and inhibition of dopamine increases the serum prolactin level (Feuchtl et al. 2004). Monoaminoxidase inhibitors, tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs) were identified as a cause of hyperprolactinemia (Wieck et al. 2004). However, data regarding hyperprolactinemia due to duloxetine, a novel serotonin-noradrenaline reuptake inhibitor, are limited (Ashton & Longdon 2007). Restless legs syndrome (RLS) is a sensorimotor disorder characterized by distressing sensations deep inside the limbs, typically occurring at bedtime or rest. These paresthesias involve an irresistible urge to move the limb, which provides temporary relief but at the expense of sleep and quality of life. RLS may be a primary or a secondary condition. Secondary causes of RLS include iron deficiency, chronic kidney disease, pregnancy, and various medications (Allen et al. 2003). In a study, RLS was noted as a possible side effect of the use of fluoxetine, paroxetine, citalopram, sertraline, escitalopram, venlafaxine, duloxetine, and mirtazapine (Rottach et al. 2008). In the present paper, we report a case of duloxetinerelated galactorrhea and restless legs syndrome." @default.
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• W48591159 date "2013-09-01" @default.
• W48591159 modified "2023-09-23" @default.
• W48591159 title "Duloxetine-related galactorrhea and restless legs syndrome: a case report." @default.
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