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- W48653522 abstract "Small and localized dissociation or perturbation on apposed membranes at a closely contacted area leads to the fusion of two membranes. The dissociation or perturbation would need to be confined to highly localized sites so that the integrity of the membranes would not be threatened. It is rational to assume that fusion-inducing mechanism of HA causes the perturbation of virus membrane as well as that of cell membrane as both membranes should be ready for fusion. Influenza virus buds from the plasma membrane of the infected cell .Thus, the parts of the infected cell membrane consist of viral envelope. If such perturbation would take place at viral parts of the membrane, the infected cell-lysis might follow. The presence or absence of NA activity did not give any significant effect on the extent of HL or cell fusion. This chapter discusses the effects of activation of HA on plasma membrane of infected cells to demonstrate that HA causes perturbation on its own base-membrane." @default.
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- W48653522 date "1984-01-01" @default.
- W48653522 modified "2023-10-16" @default.
- W48653522 title "SELF-INACTIVATION OF INFLUENZA A VIRUS AND AUTOLYSIS OF THE VIRUS-INFECTED CELLS" @default.
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- W48653522 doi "https://doi.org/10.1016/b978-0-12-183501-9.50058-3" @default.
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