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- W48838927 abstract "Probiotics have been used therapeutically and prophylactically in bacterial and fungal diseases of humans for a considerable portion of human history. Particularly targeted have been diarrhoea and other manifestations of GI infection (Clements et al. 1981; Clements et al. 1983; Steffen et al. 1986; Salminen et al. 1988), oral disease (Perrons and Donoghue 1990) and genitourinary (GU) infection (Will 1979; Sandler 1979; Bruce and Reid 1988; Nagy et al. 1991). Probiotics have also been reported to reduce cholesterol levels (Mann and Spoerry 1974; Thompson et al. 1982; Jaspers et al. 1984), prevent hepatic encephalopathy (Loguercio et al. 1987) and degrade carcinogens in the gut (Goldin et al. 1980; Cole et al. 1989). Results from these studies, however, tend to be contradictory and inconclusive (Pozo-Olano et al. 1978; Turnbull et al. 1978; Clements et al. 1981; Clements et al. 1983; Reuman et al. 1986). This uncertainty may be due to the use of preparations containing non-viable organisms, the use of microbes from a non-human source, the use of organisms which do not have the properties requisite to function as a probiotic, or to the design of the study. Horikawa (1986) demonstrated in mice that both infected and sterile burn wounds healed significantly faster when an ointment containing a heat killed strain of Lactobacillus casei was applied to the affected area and lactobacilli have been used to produce vaccines against unrelated organisms (Gombosova et al. 1986).KeywordsBacterial VaginosisLactobacillus AcidophilusLactobacillus CaseiHuman FaecesMultiple Dose StudyThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W48838927 date "1994-01-01" @default.
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- W48838927 title "Recovery of a Probiotic Organism from Human Faeces after Oral Dosing" @default.
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- W48838927 doi "https://doi.org/10.1007/978-1-4471-3443-5_8" @default.
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