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• W48853083 endingPage "479" @default.
• W48853083 startingPage "433" @default.
• W48853083 abstract "This chapter discusses calcitonin secretion. It presents the biological effects of calcitonin. Calcitonin exerts its biologic effects by acting on three primary target organs—bone, kidney, and the gastrointestinal tract. Like many other peptide hormones, calcitonin seems to mediate its effects via adenylate cyclase. The effect of calcitonin in blood is to decrease plasma calcium and phosphate concentration. The major biologic effect of calcitonin is to decrease bone resorption by inhibiting the activity of osteoclasts and osteocysts. This is reflected by the decrease in alkaline phosphatase produced by calcitonin. Calcitonin increases the urinary excretion of calcium and phosphorus. It also promotes the renal excretion of sodium and chloride and, to a lesser extent, potassium. A variety of other effects have been observed for calcitonin, such as it is anti-inflammatory, promotes fracture and wound healing, inhibits lipolysis, impairs glucose tolerance, and is an analgesic." @default.
• W48853083 created "2016-06-24" @default.
• W48853083 creator A5088158867 @default.
• W48853083 date "1982-01-01" @default.
• W48853083 modified "2023-09-24" @default.
• W48853083 title "Calcitonin Secretion" @default.
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