FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W48861127> ?p ?o ?g. }

• W48861127 abstract "The allergic reaction occurring primarily in the nasal mucosa can induce a secondary conjunctival response of an immediate (SICR), late (SLCR), or delayed (SDYCR) type in some patients with allergic conjunctivitis (AC).To investigate the concentration changes of histamine, tryptase, eosinophil cationic protein (ECP), eosinophil-derived neurotoxin (EDN), leukotrienes (LTB 4, LTC4, LTE4), myeloperoxidase (MPO), interferon-γ (IFN-γ), and interleukins (IL-2, IL-4, IL-5) in tears during the SICR, SLCR, and SDYCR.In 32 patients with AC, 11 SICR (p<0.01), 13 SLCR (p<0.001), and eight SDYCR (p<0.01) to nasal challenges with allergens (NPTs), the NPTs and 32 control tests with PBS were repeated and supplemented with the determination of these factors in tears.The SICRs were associated with significant concentration changes in tears (p<0.05) of histamine, tryptase, ECP, LTC4, and IL-4. The SLCRs were accompanied by significant changes in concentrations of histamine, ECP, LTB4, LTC4, MPO, IL-4, and IL-5. The SDYCRs were associated with significant concentration changes in tears (p<0.05) of LTB4, MPO, IFN-γ, and IL-2. No significant changes in these factors were recorded in tears during the 32 PBS controls (p>0.1) or in the ten control patients (p>0.1).These results provide evidence for causal involvement of nasal allergy in some patients with AC, inducing secondary conjunctival response of immediate (SICR), late SLCR, or delayed SDYCR type, associated with different mediator, cytokine, and cellular profiles in the tears, suggesting involvement of different hypersensitivity mechanisms. These results also emphasize the diagnostic value of nasal allergen challenge combined with monitoring of the conjunctival response in some patients with AC." @default.
• W48861127 created "2016-06-24" @default.
• W48861127 creator A5076895057 @default.
• W48861127 date "2013-01-01" @default.
• W48861127 modified "2023-09-25" @default.
• W48861127 title "Mediator profiles in tears during the conjunctival response induced by allergic reaction in the nasal mucosa." @default.
• W48861127 cites W1479076962 @default.
• W48861127 cites W1532190041 @default.
• W48861127 cites W1544465899 @default.
• W48861127 cites W1547396258 @default.
• W48861127 cites W1549652976 @default.
• W48861127 cites W1606160142 @default.
• W48861127 cites W175294427 @default.
• W48861127 cites W185501877 @default.
• W48861127 cites W1968952491 @default.
• W48861127 cites W1969332102 @default.
• W48861127 cites W1973462155 @default.
• W48861127 cites W1973620403 @default.
• W48861127 cites W1995413815 @default.
• W48861127 cites W1997103802 @default.
• W48861127 cites W2007728406 @default.
• W48861127 cites W2007814594 @default.
• W48861127 cites W2008773148 @default.
• W48861127 cites W2011796483 @default.
• W48861127 cites W2015800406 @default.
• W48861127 cites W2018002822 @default.
• W48861127 cites W2022210343 @default.
• W48861127 cites W2025001062 @default.
• W48861127 cites W2029298225 @default.
• W48861127 cites W2031298400 @default.
• W48861127 cites W2038079438 @default.
• W48861127 cites W2039999853 @default.
• W48861127 cites W2044904349 @default.
• W48861127 cites W2049394839 @default.
• W48861127 cites W2051133720 @default.
• W48861127 cites W2058798689 @default.
• W48861127 cites W2061733038 @default.
• W48861127 cites W2063088114 @default.
• W48861127 cites W2065751193 @default.
• W48861127 cites W2065819942 @default.
• W48861127 cites W2065975622 @default.
• W48861127 cites W2066262240 @default.
• W48861127 cites W2071745274 @default.
• W48861127 cites W2078512506 @default.
• W48861127 cites W2080084796 @default.
• W48861127 cites W2081781694 @default.
• W48861127 cites W2082952072 @default.
• W48861127 cites W2083714440 @default.
• W48861127 cites W2084241991 @default.
• W48861127 cites W2086626460 @default.
• W48861127 cites W2090062323 @default.
• W48861127 cites W2100022920 @default.
• W48861127 cites W2117430123 @default.
• W48861127 cites W2130614990 @default.
• W48861127 cites W2133325478 @default.
• W48861127 cites W2157016916 @default.
• W48861127 cites W2158409323 @default.
• W48861127 cites W2164766687 @default.
• W48861127 cites W2170425364 @default.
• W48861127 cites W2317481954 @default.
• W48861127 cites W2324210116 @default.
• W48861127 cites W2338637103 @default.
• W48861127 cites W2415018006 @default.
• W48861127 cites W2476498053 @default.
• W48861127 cites W2477097161 @default.
• W48861127 cites W2486300890 @default.
• W48861127 cites W2487742422 @default.
• W48861127 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3712666" @default.
• W48861127 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23869165" @default.
• W48861127 hasPublicationYear "2013" @default.
• W48861127 type Work @default.
• W48861127 sameAs 48861127 @default.
• W48861127 citedByCount "5" @default.
• W48861127 countsByYear W488611272015 @default.
• W48861127 countsByYear W488611272017 @default.
• W48861127 countsByYear W488611272018 @default.
• W48861127 countsByYear W488611272019 @default.
• W48861127 crossrefType "journal-article" @default.
• W48861127 hasAuthorship W48861127A5076895057 @default.
• W48861127 hasConcept C1122143 @default.
• W48861127 hasConcept C126322002 @default.
• W48861127 hasConcept C141105273 @default.
• W48861127 hasConcept C159654299 @default.
• W48861127 hasConcept C203014093 @default.
• W48861127 hasConcept C203565725 @default.
• W48861127 hasConcept C207480886 @default.
• W48861127 hasConcept C2776042228 @default.
• W48861127 hasConcept C2776914184 @default.
• W48861127 hasConcept C2776953665 @default.
• W48861127 hasConcept C2777037409 @default.
• W48861127 hasConcept C2778081958 @default.
• W48861127 hasConcept C2778275304 @default.
• W48861127 hasConcept C2778690821 @default.
• W48861127 hasConcept C2779675166 @default.
• W48861127 hasConcept C2779726688 @default.
• W48861127 hasConcept C2780510475 @default.
• W48861127 hasConcept C2780870513 @default.
• W48861127 hasConcept C2781406822 @default.
• W48861127 hasConcept C59377437 @default.
• W48861127 hasConcept C71924100 @default.

• next