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- W49009717 abstract "Objective To observe the cytotoxicity of chymopapain combined with pingyangmycin (PYM) on mouse hepatoma cell line hapa-6 in vitro. Method MTT method. Results Chymopapain showed cytotoxicities to hepa-6 (IC50 is about 1200 microg/ml) and had concentration dependency. Cooperation effect was showed when three different concentration chymopapain combined with PYM during 48 hours. It accorded with the change of enzyme activity of chymopapain in saline water. Cooperation effect was showed again when adding chymopapin for the second time at 48 hours. Conclusion Chymopapain has cytotoxicity on hepa-6 in vitro. Cooperation effect was showed when chymopapin was combined with PYM." @default.
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- W49009717 date "2004-04-01" @default.
- W49009717 modified "2023-09-28" @default.
- W49009717 title "[Cytotoxicity of chymopapain combined with pingyangmycin on mouse hepatoma cell line hepa-6]." @default.
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