Matches in SemOpenAlex for { <https://semopenalex.org/work/W4936268> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W4936268 endingPage "5" @default.
- W4936268 startingPage "S92" @default.
- W4936268 abstract "The late effects of cancer treatment in children diagnosed early in life (under 2 years of age) may be compared to those in children who were over 2 years at the time of diagnosis. Such areas as growth and development (e.g., intellectual and sexual), vital organ function and risk for second cancer are of particular interest. This report reviews late occurring morbidity which was studied in approximately 400 survivors of childhood cancer, 93 of whom were under 2 years of age at diagnosis. The most commonly reported late effect was musculoskeletal in radiation treated patients. More severe cognitive deficits were seen among both age groups cranially irradiated for leukaemia prophylaxis with 24 Gy compared to 18 Gy. Second cancers developed equally between the two age groups. Predisposing factors and/or prior therapy may produce second cancers. There are inherent problems in assessing the outcomes of very young children treated for cancer. Improved survival has only been evident during the last 15 years, a period too short to appreciate many of the end points of interest in adult life. Such patients require a necessarily long follow-up period but this will prove informative in the future as more institutions initiate procedures for extended surveillance." @default.
- W4936268 created "2016-06-24" @default.
- W4936268 creator A5000471996 @default.
- W4936268 creator A5027785317 @default.
- W4936268 creator A5060643132 @default.
- W4936268 date "1992-08-01" @default.
- W4936268 modified "2023-10-14" @default.
- W4936268 title "Late effects of early childhood cancer therapy." @default.
- W4936268 cites W1763756323 @default.
- W4936268 cites W2007023752 @default.
- W4936268 cites W2020074406 @default.
- W4936268 cites W2025631528 @default.
- W4936268 cites W2043894837 @default.
- W4936268 cites W2055558717 @default.
- W4936268 cites W2060658196 @default.
- W4936268 cites W2099742439 @default.
- W4936268 cites W2320188351 @default.
- W4936268 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2149648" @default.
- W4936268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1503934" @default.
- W4936268 hasPublicationYear "1992" @default.
- W4936268 type Work @default.
- W4936268 sameAs 4936268 @default.
- W4936268 citedByCount "8" @default.
- W4936268 countsByYear W49362682013 @default.
- W4936268 countsByYear W49362682015 @default.
- W4936268 countsByYear W49362682019 @default.
- W4936268 crossrefType "journal-article" @default.
- W4936268 hasAuthorship W4936268A5000471996 @default.
- W4936268 hasAuthorship W4936268A5027785317 @default.
- W4936268 hasAuthorship W4936268A5060643132 @default.
- W4936268 hasConcept C121608353 @default.
- W4936268 hasConcept C126322002 @default.
- W4936268 hasConcept C141071460 @default.
- W4936268 hasConcept C178640370 @default.
- W4936268 hasConcept C187212893 @default.
- W4936268 hasConcept C2992894027 @default.
- W4936268 hasConcept C509974204 @default.
- W4936268 hasConcept C71924100 @default.
- W4936268 hasConceptScore W4936268C121608353 @default.
- W4936268 hasConceptScore W4936268C126322002 @default.
- W4936268 hasConceptScore W4936268C141071460 @default.
- W4936268 hasConceptScore W4936268C178640370 @default.
- W4936268 hasConceptScore W4936268C187212893 @default.
- W4936268 hasConceptScore W4936268C2992894027 @default.
- W4936268 hasConceptScore W4936268C509974204 @default.
- W4936268 hasConceptScore W4936268C71924100 @default.
- W4936268 hasLocation W49362681 @default.
- W4936268 hasOpenAccess W4936268 @default.
- W4936268 hasPrimaryLocation W49362681 @default.
- W4936268 hasRelatedWork W1972284841 @default.
- W4936268 hasRelatedWork W1984124704 @default.
- W4936268 hasRelatedWork W2040228556 @default.
- W4936268 hasRelatedWork W2101145739 @default.
- W4936268 hasRelatedWork W2338610038 @default.
- W4936268 hasRelatedWork W2355621911 @default.
- W4936268 hasRelatedWork W2606731821 @default.
- W4936268 hasRelatedWork W2809256484 @default.
- W4936268 hasRelatedWork W3111217149 @default.
- W4936268 hasRelatedWork W4251386743 @default.
- W4936268 hasVolume "18" @default.
- W4936268 isParatext "false" @default.
- W4936268 isRetracted "false" @default.
- W4936268 magId "4936268" @default.
- W4936268 workType "article" @default.