Matches in SemOpenAlex for { <https://semopenalex.org/work/W49434876> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W49434876 abstract "Avascular tissues such as articular cartilage and intervertebral disc have limited capacity to regenerate themselves due to their avascular nature. Some patients may benefit from surgical procedures such as spinal fusion or knee arthroplasties. However, these treatments don’t restore joint flexibility and metal is a poor substitute for healthy biological tissues. These downfalls increase the demand on novel strategies for artificial cartilage and intervertebral disc. One of the major functions of avascular tissue is to withstand mechanical loads that are generated in the body during daily activities and transfer them to bones through joints. In vitro tests based on the hypothesis of mechanosensitivity demonstrated that the metabolic activities in cell seeded constructs can be regulated via physiologic loading. However, primary mechanical influences that regulate these cellular processes are still unclear. This study aims at identifying the mechanical parameters that contribute to cellular metabolism of chondrocyte seeded constructs during physiological loading. Determined factors could then be used to optimize matrix protein synthesis, proliferation and nitric oxide release for tissue engineering applications." @default.
- W49434876 created "2016-06-24" @default.
- W49434876 creator A5019559523 @default.
- W49434876 creator A5055249375 @default.
- W49434876 creator A5055346737 @default.
- W49434876 date "2009-01-01" @default.
- W49434876 modified "2023-09-27" @default.
- W49434876 title "Numerical assessment on the metabolic response of chondrocytes after cyclic loading: The influence of stress rate and magnitude" @default.
- W49434876 cites W147647137 @default.
- W49434876 cites W1966291445 @default.
- W49434876 cites W2050535146 @default.
- W49434876 cites W2064061432 @default.
- W49434876 cites W2168114618 @default.
- W49434876 doi "https://doi.org/10.1007/978-3-642-03900-3_77" @default.
- W49434876 hasPublicationYear "2009" @default.
- W49434876 type Work @default.
- W49434876 sameAs 49434876 @default.
- W49434876 citedByCount "1" @default.
- W49434876 crossrefType "book-chapter" @default.
- W49434876 hasAuthorship W49434876A5019559523 @default.
- W49434876 hasAuthorship W49434876A5055249375 @default.
- W49434876 hasAuthorship W49434876A5055346737 @default.
- W49434876 hasConcept C105702510 @default.
- W49434876 hasConcept C105795698 @default.
- W49434876 hasConcept C126322002 @default.
- W49434876 hasConcept C136229726 @default.
- W49434876 hasConcept C185592680 @default.
- W49434876 hasConcept C2777755357 @default.
- W49434876 hasConcept C2780550940 @default.
- W49434876 hasConcept C2780598303 @default.
- W49434876 hasConcept C2781403057 @default.
- W49434876 hasConcept C33923547 @default.
- W49434876 hasConcept C519581460 @default.
- W49434876 hasConcept C71924100 @default.
- W49434876 hasConcept C86803240 @default.
- W49434876 hasConcept C95444343 @default.
- W49434876 hasConceptScore W49434876C105702510 @default.
- W49434876 hasConceptScore W49434876C105795698 @default.
- W49434876 hasConceptScore W49434876C126322002 @default.
- W49434876 hasConceptScore W49434876C136229726 @default.
- W49434876 hasConceptScore W49434876C185592680 @default.
- W49434876 hasConceptScore W49434876C2777755357 @default.
- W49434876 hasConceptScore W49434876C2780550940 @default.
- W49434876 hasConceptScore W49434876C2780598303 @default.
- W49434876 hasConceptScore W49434876C2781403057 @default.
- W49434876 hasConceptScore W49434876C33923547 @default.
- W49434876 hasConceptScore W49434876C519581460 @default.
- W49434876 hasConceptScore W49434876C71924100 @default.
- W49434876 hasConceptScore W49434876C86803240 @default.
- W49434876 hasConceptScore W49434876C95444343 @default.
- W49434876 hasLocation W494348761 @default.
- W49434876 hasOpenAccess W49434876 @default.
- W49434876 hasPrimaryLocation W494348761 @default.
- W49434876 hasRelatedWork W1513444254 @default.
- W49434876 hasRelatedWork W15616638 @default.
- W49434876 hasRelatedWork W19624625 @default.
- W49434876 hasRelatedWork W2004802368 @default.
- W49434876 hasRelatedWork W2009840300 @default.
- W49434876 hasRelatedWork W2055316184 @default.
- W49434876 hasRelatedWork W2056125499 @default.
- W49434876 hasRelatedWork W2065398254 @default.
- W49434876 hasRelatedWork W2090421014 @default.
- W49434876 hasRelatedWork W2091025894 @default.
- W49434876 hasRelatedWork W2146994640 @default.
- W49434876 hasRelatedWork W2157217893 @default.
- W49434876 hasRelatedWork W2182452829 @default.
- W49434876 hasRelatedWork W2194153844 @default.
- W49434876 hasRelatedWork W2301990320 @default.
- W49434876 hasRelatedWork W2337583466 @default.
- W49434876 hasRelatedWork W2389187459 @default.
- W49434876 hasRelatedWork W2461475616 @default.
- W49434876 hasRelatedWork W3010715453 @default.
- W49434876 hasRelatedWork W3200474554 @default.
- W49434876 isParatext "false" @default.
- W49434876 isRetracted "false" @default.
- W49434876 magId "49434876" @default.
- W49434876 workType "book-chapter" @default.