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- W49538369 abstract "Spectrophotometric and conductometric determination of haloperidol (HAL), droperidol (DRO) and pimozide (PIM) has been described. Spectrophotometric method is based on the reaction of HAL and PIM with [Cr(NCS) 6 ] 3 - , [BiI 6 ] 3 - and picric acid (PA). Calibration plots are consistent with Beer's law in the following concentration ranges: 0.15-1.14 and 0.18-2.68 μg mL - 1 for HAL and PIM with [Cr(NCS) 6 ] 3 - ; 0.21-1.57 μg mL - 1 for HAL with [BiI 6 ] 3 - , and 0.06-0.91 μg mL-' and 0.07-0.7 μg mL-' with PA for HAL and PIM, respectively. Conductometric titrations were performed with (NH 4 ) 6 Mo 7 O 2 4 , NaVO 3 and NaAsO 2 as titrants. The proposed methods are accurate and precise with the relative standard deviation less than 1%. One used 2.5-12.5 mg of each pharmaceutic, depending on the titrant applied. The conductometric titrimetry can be successfully applied to the determination of the studied drugs in commercial preparations." @default.
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- W49538369 date "2004-01-01" @default.
- W49538369 modified "2023-09-23" @default.
- W49538369 title "Conductometric and spectrophotometric determination of haloperidol, droperidol and pimozide" @default.
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