FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4961763> ?p ?o ?g. }

• W4961763 endingPage "4572" @default.
• W4961763 startingPage "4572" @default.
• W4961763 abstract "To study the effects of chitosan gel and blending chiston/gelatin film on preventing peritoneal adhesion in rats.SD rats were randomly divided into 2 groups, group A treated with chitosan gel and group B with blending chiston/gelatin film. In group A, rats were randomly subdivided into 3 subgroups as groups A1, A2 and A3, and different methods were used to induce peritoneal adhesions at the dead end of vermiform process in each group as follows: Group A1 with trauma, A2 with talc powder and A3 with ligation of blood vessel. In each subgroup, rats were redivided into control group and experimental group whose treated vermiform processes were respectively coated with chitosan gel and normal saline immediately after the adhesion-induced treatments. In group B, all the rats received traumatic adhesion-induced treatments and then were randomly divided into 4 groups (groups B1, B2, B3, B4). Group B1 served as control group and were coated with normal saline in the vermiform processes immediately after the treatments, and groups B2, B3 and B4 with 100% chitosan film, chitosan film containing 10% gelatin and chiston film containing 50% gelatin, respectively. At 2 and 4 wk after the above treatments, half of the rats in each terminal group were belly opened, and the peritoneal adhesive situation was graded and histopathological changes were examined.(1) In group A, regarding peritoneal adhesion situation: At both 2 and 4 wk after the treatments, for groups A1 and A3, the adhesive grades of experimental groups were significantly lower than those of the control group (2 wk: H = 4.305, P < 0.05 for A1, H = 6.743, P < 0.01 for A3; 4 wk: H = 4.459, P < 0.05 for A1, H = 4.493, P < 0.05 for A3). However, of group A2, there was no significant difference between the experimental and control groups (2 wk: H = 0.147, P > 0.05; 4 wk: H = 1.240, P > 0.05). Regarding pathological changes: In groups A1 and A3, the main pathological change was fibroplasia. In group A2, the main changes were massive foreign-body giant cell reaction and granuloma formation with fibroplasia of different degrees. (2) In group B, regarding degradation of film: With increase of the blended gelatin concentration, degrading speed of the film accelerated significantly. Regarding peritoneal adhesion situation: At both 2 and 4 wk after the treatments, the adhesive grades of B1 were the lowest among the four subgroups of B (2 wk: H = 29.679, P < 0.05; 4 wk: H = 18.791, P < 0.05). At 2 wk after the treatments, the grades of group B2 were significantly lower than that of groups B3 and B4 (H = 4.025, P < 0.05 for B2 vs B3; H = 4.361, P < 0.05 for B2 vs B4). At 4 wk, there were no significant differences of the grades between groups B2, B3 and B4. Regarding pathological changes: Inflammatory cell infiltration and fibroplastic proliferation were observed in the local treated serous membranes, which was the mildest in group B1. Slight foreign-body giant cell reactions were also found in groups B2, B3, and B4.(1) Chitosan gel has preventive effect on traumatic or ischemic peritoneal adhesion, but no obvious effect on foreign body-induced peritoneal adhesion. (2) Chitosan film may exacerbate the peritoneal adhesion. Blending with gelatin to chitosan film can accelerate the degradation of the film, but can simultaneously facilitate the formation of peritoneal adhesion." @default.
• W4961763 created "2016-06-24" @default.
• W4961763 creator A5002648033 @default.
• W4961763 creator A5059519440 @default.
• W4961763 creator A5081706069 @default.
• W4961763 date "2006-01-01" @default.
• W4961763 modified "2023-10-05" @default.
• W4961763 title "Preventive effects of chitosan on peritoneal adhesion in rats" @default.
• W4961763 cites W153145143 @default.
• W4961763 cites W1883215304 @default.
• W4961763 cites W1964187916 @default.
• W4961763 cites W1978288927 @default.
• W4961763 cites W2024276796 @default.
• W4961763 cites W2028308616 @default.
• W4961763 cites W2061202690 @default.
• W4961763 cites W2076314136 @default.
• W4961763 cites W2105810016 @default.
• W4961763 doi "https://doi.org/10.3748/wjg.v12.i28.4572" @default.
• W4961763 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4125651" @default.
• W4961763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16874876" @default.
• W4961763 hasPublicationYear "2006" @default.
• W4961763 type Work @default.
• W4961763 sameAs 4961763 @default.
• W4961763 citedByCount "33" @default.
• W4961763 countsByYear W49617632012 @default.
• W4961763 countsByYear W49617632013 @default.
• W4961763 countsByYear W49617632014 @default.
• W4961763 countsByYear W49617632015 @default.
• W4961763 countsByYear W49617632017 @default.
• W4961763 countsByYear W49617632018 @default.
• W4961763 countsByYear W49617632019 @default.
• W4961763 countsByYear W49617632023 @default.
• W4961763 crossrefType "journal-article" @default.
• W4961763 hasAuthorship W4961763A5002648033 @default.
• W4961763 hasAuthorship W4961763A5059519440 @default.
• W4961763 hasAuthorship W4961763A5081706069 @default.
• W4961763 hasBestOaLocation W49617631 @default.
• W4961763 hasConcept C126322002 @default.
• W4961763 hasConcept C141071460 @default.
• W4961763 hasConcept C151730666 @default.
• W4961763 hasConcept C178790620 @default.
• W4961763 hasConcept C185592680 @default.
• W4961763 hasConcept C2776364125 @default.
• W4961763 hasConcept C2777397205 @default.
• W4961763 hasConcept C2778823387 @default.
• W4961763 hasConcept C2779732960 @default.
• W4961763 hasConcept C2780678043 @default.
• W4961763 hasConcept C2781345968 @default.
• W4961763 hasConcept C55493867 @default.
• W4961763 hasConcept C71924100 @default.
• W4961763 hasConcept C84416704 @default.
• W4961763 hasConcept C86803240 @default.
• W4961763 hasConceptScore W4961763C126322002 @default.
• W4961763 hasConceptScore W4961763C141071460 @default.
• W4961763 hasConceptScore W4961763C151730666 @default.
• W4961763 hasConceptScore W4961763C178790620 @default.
• W4961763 hasConceptScore W4961763C185592680 @default.
• W4961763 hasConceptScore W4961763C2776364125 @default.
• W4961763 hasConceptScore W4961763C2777397205 @default.
• W4961763 hasConceptScore W4961763C2778823387 @default.
• W4961763 hasConceptScore W4961763C2779732960 @default.
• W4961763 hasConceptScore W4961763C2780678043 @default.
• W4961763 hasConceptScore W4961763C2781345968 @default.
• W4961763 hasConceptScore W4961763C55493867 @default.
• W4961763 hasConceptScore W4961763C71924100 @default.
• W4961763 hasConceptScore W4961763C84416704 @default.
• W4961763 hasConceptScore W4961763C86803240 @default.
• W4961763 hasIssue "28" @default.
• W4961763 hasLocation W49617631 @default.
• W4961763 hasLocation W49617632 @default.
• W4961763 hasLocation W49617633 @default.
• W4961763 hasLocation W49617634 @default.
• W4961763 hasOpenAccess W4961763 @default.
• W4961763 hasPrimaryLocation W49617631 @default.
• W4961763 hasRelatedWork W2004194677 @default.
• W4961763 hasRelatedWork W2009300804 @default.
• W4961763 hasRelatedWork W2352474990 @default.
• W4961763 hasRelatedWork W2363834387 @default.
• W4961763 hasRelatedWork W2387336222 @default.
• W4961763 hasRelatedWork W2389466319 @default.
• W4961763 hasRelatedWork W2391434834 @default.
• W4961763 hasRelatedWork W2588094306 @default.
• W4961763 hasRelatedWork W3020864060 @default.
• W4961763 hasRelatedWork W4368363754 @default.
• W4961763 hasVolume "12" @default.
• W4961763 isParatext "false" @default.
• W4961763 isRetracted "false" @default.
• W4961763 magId "4961763" @default.
• W4961763 workType "article" @default.