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- W49662332 abstract "No AccessJournal of Urology1 Aug 1983In Vivo Staining Test with Methylene Blue for Bladder Cancer I. Fukui, M. Yokokawa, G. Mitani, F. Ohwada, M. Wakui, M. Washizuka, T. Tohma, K. Igarashi, and T. Yamada I. FukuiI. Fukui More articles by this author , M. YokokawaM. Yokokawa More articles by this author , G. MitaniG. Mitani More articles by this author , F. OhwadaF. Ohwada More articles by this author , M. WakuiM. Wakui More articles by this author , M. WashizukaM. Washizuka More articles by this author , T. TohmaT. Tohma More articles by this author , K. IgarashiK. Igarashi More articles by this author , and T. YamadaT. Yamada More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)51088-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail An in vivo staining test with 0.2 per cent methylene blue was applied to 129 patients with bladder tumor and 16 patients with chronic cystitis within a 6-year interval. Although normal mucosa did not pick up the stain nonpapillary in situ and microinvasive carcinomas did so frequently. Moderate dysplasia was stained in about half of the patients. The intensity of the stain in papillary tumors was correlated with the histologic anaplasia (grade). Grade 1 tumors were stained poorly or unstained in 86 per cent of the tests, whereas grades 2 and 3 tumors picked up the stain in 74 and 96 per cent of the tests, respectively. Even a tiny tumor, if poorly differentiated, was identified easily by the blue stain. The histologic anaplasia of tumors could be assessed roughly according to the intensity of the stain. However, chronic cystitis occasionally took up the stain, especially in cases of marked inflammatory infiltrate a deep stain was recognized. To differentiate nonpapillary early cancer from chronic cystitis the addition of a cytologic examination may be necessary. © 1983 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByPontes J (2018) Editorial: Bladder CancerJournal of Urology, VOL. 156, NO. 5, (1609-1610), Online publication date: 1-Nov-1996.Yu D, Chang S and Ma C (2018) Photoinactivation of Bladder Tumor Cells by Methylene Blue: Study of a Variety of Tumor and Normal CellsJournal of Urology, VOL. 144, NO. 1, (164-168), Online publication date: 1-Jul-1990. Volume 130Issue 2August 1983Page: 252-254 Advertisement Copyright & Permissions© 1983 by The American Urological Association Education and Research, Inc.MetricsAuthor Information I. Fukui More articles by this author M. Yokokawa More articles by this author G. Mitani More articles by this author F. Ohwada More articles by this author M. Wakui More articles by this author M. Washizuka More articles by this author T. Tohma More articles by this author K. Igarashi More articles by this author T. Yamada More articles by this author Expand All Advertisement Loading ..." @default.
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- W49662332 date "1983-08-01" @default.
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- W49662332 title "In Vivo Staining Test with Methylene Blue for Bladder Cancer" @default.
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