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- W50184766 abstract "The existence of left- or right-handedness of a compound is referred to as chirality. Each form (left- or right-handed) of a chiral compound is called an 'enantiomer' or an 'isomer'. A collection containing only one enantiomeric form of a chiral molecule is called an optically pure, chirally pure, enantiomerically pure or unichiral compound while collection of equal amounts of the two enantiomeric forms (R and S) is called a racemate. Many of the drugs currently used in medical practice are racemates. However it is well documented that the two enantiomers of a racemate can differ in their pharmacokinetic/pharmacodynamic and efficacy/ safety profiles. Replacing existing racemates with unichiral drugs may result in improved safety and/or efficacy profile of various racemates. This article presents an overview of differential properties of enantiomers of some commercially available racemates." @default.
- W50184766 created "2016-06-24" @default.
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- W50184766 date "2007-04-01" @default.
- W50184766 modified "2023-09-23" @default.
- W50184766 title "Differential properties of enantiomers of commercially available racemates." @default.
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