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- W50268188 endingPage "794" @default.
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- W50268188 abstract "Menaopause is the stage which marks the end of an important physiological system of the body thus largely impacting the release of pituitary and gonadal hormones. Menopause has also been termed as the consequence of Ovarian failure, as the perimenopausal period is distinctly marked by a decrease in the number of ovarian follicles and an increase in the FSH secretion. This chapter illustrates the anatomical studies on the gonadotropin-releasing hormone neurons in the hypothalamus of primates and their Basal Forebrain. Neuronal hypertrophy has also been studied in the post menopausal women. Secretions of endogenous opioids play a significant role in the secretion of gonadotropin in human beings. Studies have also revealed that menopause is related to the decline in the count of neurons that express Proopiomelanocortin messenger RNAs found in the human Infundibular Nucleus. Studies have shown a strong association between the number of neurons expressing Proopiomelanocortin gene transcripts and the age of the women on whom the studies were conducted. It has thus been established that menopause is the cumulative outcome of ovarian failure, gonadotropin hypersecretion, and major changes in morphology and neuropeptide gene expression in the medial basal hypothalamus." @default.
- W50268188 created "2016-06-24" @default.
- W50268188 creator A5023412429 @default.
- W50268188 creator A5038977510 @default.
- W50268188 date "2001-01-01" @default.
- W50268188 modified "2023-09-25" @default.
- W50268188 title "Hypothalamic Neuropeptide Gene Expression in Postmenopausal Women" @default.
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