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- W5061914 abstract "MAC infection has several clinical manifestations. This is one of the most common opportunistic pathogens in AIDS patients with CD4+ cell counts less than 50 cells/mm3. MAC also causes pulmonary, soft tissue, and bone or joint infections in immunocompetent patients. When repeatedly isolated from the sputum in a patient with a compatible clinical picture or when isolated from a normally sterile site, MAC should be considered as a pathogen and treated with a minimum of three antimycobacterial drugs. In certain cases of extensive, localized infection, surgery may be a necessary adjunct to medical therapy. Childhood lymphadenitis caused by MAC is usually cured by simple excision without a requirement for antimicrobial therapy. In contrast, MAC infection in AIDS patients is often disseminated and requires prolonged (if not life-long) therapy with multiple medications. Antibiotic prophylaxis may be useful for prevention of MAC infections in AIDS patients with low CD4+ cells counts." @default.
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- W5061914 title "Chapter 10 Mycobacterium avium-intercellulare (MAI)" @default.
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- W5061914 doi "https://doi.org/10.1016/s1569-2582(97)80147-x" @default.
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