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- W50828552 abstract "The ability to predict the genetic consequences for humans of exposure to ionising radiation has certainly been one of the most important goals of human genetics in the past fifty years. However, despite numerous experimental studies, little is known about the effects of radiation exposure on germline mutation in humans. For example, data collected in Hiroshima and Nagasaki during the past 40 years on children of atomic bomb survivors using standard monitoring systems have not provided evidence of any statistically signifycant differences in mutation rate between exposed and control families (Neel at al., 1990). Similarly, a survey of survivors treated with radiotherapy showed that the occurrence of genetic diseases in their offspring was similar to that in control families (Byrne et al, 1998). For this reason, germline mutation induction in mice still remains the main source of experimental data used to evaluate the genetic risk of human exposure to ionising radiation (UNCEAR, 1993; Sankaranarayanan and Chakraborty, 2000)." @default.
- W50828552 created "2016-06-24" @default.
- W50828552 creator A5063733515 @default.
- W50828552 date "2003-01-01" @default.
- W50828552 modified "2023-10-18" @default.
- W50828552 title "Germline Mutation Induction at Mouse and Human Tandem Repeat DNA Loci" @default.
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- W50828552 doi "https://doi.org/10.1007/978-1-4419-9190-4_10" @default.
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