Matches in SemOpenAlex for { <https://semopenalex.org/work/W51178316> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W51178316 endingPage "6" @default.
- W51178316 startingPage "1004" @default.
- W51178316 abstract "Aripiprazole is a new drug applied in schizophrenia treatment. There are not strict indications for aripiprazole therapeutic drug monitoring. Despite, serum aripiprazole measuring would help control the drug doses effectiveness. The drug monitoring can eliminate overdosing, adverse effects and let control proper drug ingestion. The aim of the paper was to develop a simple method for aripiprazole determination in serum for therapeutic drug monitoring. High performance liquid chromatography with spectrophotometric detection (HPLC-UV) was used. Resolution was performed on LC-8 column; moving phase was solution 0,025M trimethylammonium buffer: acetonitrile (62:38). Isocratic flow was 1,2 ml/min; internal standard (IS) was promazine; monitored wavelength was lambda=214 nm. The validation parameters were: limits of linearity (LOL) 100-800 ng/ml, limit of detection (LOD) 10 ng/ml, limit of quantity (LOQ) 100 ng/ml. Coefficient of variation (CV) describing accuracy and precision didn't cross 10%. The method was useful for therapeutic drug monitoring in serum of patients treated with aripiprazole." @default.
- W51178316 created "2016-06-24" @default.
- W51178316 creator A5005540958 @default.
- W51178316 creator A5012538246 @default.
- W51178316 creator A5054696688 @default.
- W51178316 creator A5060903244 @default.
- W51178316 creator A5074907745 @default.
- W51178316 creator A5087672473 @default.
- W51178316 date "2012-01-01" @default.
- W51178316 modified "2023-10-12" @default.
- W51178316 title "[Application of HPLC-UV method for aripiprazole determination in serum]." @default.
- W51178316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23421079" @default.
- W51178316 hasPublicationYear "2012" @default.
- W51178316 type Work @default.
- W51178316 sameAs 51178316 @default.
- W51178316 citedByCount "0" @default.
- W51178316 crossrefType "journal-article" @default.
- W51178316 hasAuthorship W51178316A5005540958 @default.
- W51178316 hasAuthorship W51178316A5012538246 @default.
- W51178316 hasAuthorship W51178316A5054696688 @default.
- W51178316 hasAuthorship W51178316A5060903244 @default.
- W51178316 hasAuthorship W51178316A5074907745 @default.
- W51178316 hasAuthorship W51178316A5087672473 @default.
- W51178316 hasConcept C118552586 @default.
- W51178316 hasConcept C119128265 @default.
- W51178316 hasConcept C179998833 @default.
- W51178316 hasConcept C185592680 @default.
- W51178316 hasConcept C2776412080 @default.
- W51178316 hasConcept C2780035454 @default.
- W51178316 hasConcept C2780211496 @default.
- W51178316 hasConcept C2780272996 @default.
- W51178316 hasConcept C43617362 @default.
- W51178316 hasConcept C71924100 @default.
- W51178316 hasConcept C98274493 @default.
- W51178316 hasConceptScore W51178316C118552586 @default.
- W51178316 hasConceptScore W51178316C119128265 @default.
- W51178316 hasConceptScore W51178316C179998833 @default.
- W51178316 hasConceptScore W51178316C185592680 @default.
- W51178316 hasConceptScore W51178316C2776412080 @default.
- W51178316 hasConceptScore W51178316C2780035454 @default.
- W51178316 hasConceptScore W51178316C2780211496 @default.
- W51178316 hasConceptScore W51178316C2780272996 @default.
- W51178316 hasConceptScore W51178316C43617362 @default.
- W51178316 hasConceptScore W51178316C71924100 @default.
- W51178316 hasConceptScore W51178316C98274493 @default.
- W51178316 hasIssue "10" @default.
- W51178316 hasLocation W511783161 @default.
- W51178316 hasOpenAccess W51178316 @default.
- W51178316 hasPrimaryLocation W511783161 @default.
- W51178316 hasRelatedWork W1913148260 @default.
- W51178316 hasRelatedWork W1998279148 @default.
- W51178316 hasRelatedWork W2013299392 @default.
- W51178316 hasRelatedWork W2032191029 @default.
- W51178316 hasRelatedWork W2046276537 @default.
- W51178316 hasRelatedWork W2073353646 @default.
- W51178316 hasRelatedWork W2080191601 @default.
- W51178316 hasRelatedWork W2588622224 @default.
- W51178316 hasRelatedWork W3029450219 @default.
- W51178316 hasRelatedWork W3085245795 @default.
- W51178316 hasVolume "69" @default.
- W51178316 isParatext "false" @default.
- W51178316 isRetracted "false" @default.
- W51178316 magId "51178316" @default.
- W51178316 workType "article" @default.