Matches in SemOpenAlex for { <https://semopenalex.org/work/W5130003> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W5130003 endingPage "52" @default.
- W5130003 startingPage "647" @default.
- W5130003 abstract "Although cathepsin D has been implicated in prostate cancer invasion and metastasis, the distribution of this enzyme in normal human prostate is unknown. We investigated immunohistochemically the distribution of cathepsin D granules in normal prostatic tissues with or without androgen ablation. We also examined the cancer tissues after androgen ablation and the hyperplastic tissues. Changes in the distribution pattern of the larger cathepsin D-positive granules (apoptotic bodies) were observed in the normal prostate as well as in the normal tissue of the anti-androgen-treated cancer specimens. While the apoptotic bodies were denser in the proximal duct of the normal adult prostate, they were more abundant in the normal peripheral acini of the anti-androgen-treated cases. There were few apoptotic bodies in the adenoma tissues, but many in the hormonally treated cancer tissues. These results showed that the distribution pattern and density of cathepsin D granules well reflected the status of the human prostatic cells in relation to age, hormonal environment and hyperplastic or neoplastic change." @default.
- W5130003 created "2016-06-24" @default.
- W5130003 creator A5009964177 @default.
- W5130003 creator A5060605076 @default.
- W5130003 creator A5079406972 @default.
- W5130003 creator A5091264322 @default.
- W5130003 date "2002-11-01" @default.
- W5130003 modified "2023-09-23" @default.
- W5130003 title "Distribution of cathepsin D granules in normal and pathologic conditions in human prostate." @default.
- W5130003 cites W1980838439 @default.
- W5130003 cites W2005010706 @default.
- W5130003 cites W2187176260 @default.
- W5130003 cites W2323851785 @default.
- W5130003 cites W2429615038 @default.
- W5130003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12512135" @default.
- W5130003 hasPublicationYear "2002" @default.
- W5130003 type Work @default.
- W5130003 sameAs 5130003 @default.
- W5130003 citedByCount "1" @default.
- W5130003 crossrefType "journal-article" @default.
- W5130003 hasAuthorship W5130003A5009964177 @default.
- W5130003 hasAuthorship W5130003A5060605076 @default.
- W5130003 hasAuthorship W5130003A5079406972 @default.
- W5130003 hasAuthorship W5130003A5091264322 @default.
- W5130003 hasConcept C121608353 @default.
- W5130003 hasConcept C126322002 @default.
- W5130003 hasConcept C134018914 @default.
- W5130003 hasConcept C142724271 @default.
- W5130003 hasConcept C167844969 @default.
- W5130003 hasConcept C173633252 @default.
- W5130003 hasConcept C181199279 @default.
- W5130003 hasConcept C2776235491 @default.
- W5130003 hasConcept C2777428134 @default.
- W5130003 hasConcept C2777562237 @default.
- W5130003 hasConcept C2777911890 @default.
- W5130003 hasConcept C2780192828 @default.
- W5130003 hasConcept C55493867 @default.
- W5130003 hasConcept C71315377 @default.
- W5130003 hasConcept C71924100 @default.
- W5130003 hasConcept C86803240 @default.
- W5130003 hasConceptScore W5130003C121608353 @default.
- W5130003 hasConceptScore W5130003C126322002 @default.
- W5130003 hasConceptScore W5130003C134018914 @default.
- W5130003 hasConceptScore W5130003C142724271 @default.
- W5130003 hasConceptScore W5130003C167844969 @default.
- W5130003 hasConceptScore W5130003C173633252 @default.
- W5130003 hasConceptScore W5130003C181199279 @default.
- W5130003 hasConceptScore W5130003C2776235491 @default.
- W5130003 hasConceptScore W5130003C2777428134 @default.
- W5130003 hasConceptScore W5130003C2777562237 @default.
- W5130003 hasConceptScore W5130003C2777911890 @default.
- W5130003 hasConceptScore W5130003C2780192828 @default.
- W5130003 hasConceptScore W5130003C55493867 @default.
- W5130003 hasConceptScore W5130003C71315377 @default.
- W5130003 hasConceptScore W5130003C71924100 @default.
- W5130003 hasConceptScore W5130003C86803240 @default.
- W5130003 hasIssue "11" @default.
- W5130003 hasLocation W51300031 @default.
- W5130003 hasOpenAccess W5130003 @default.
- W5130003 hasPrimaryLocation W51300031 @default.
- W5130003 hasRelatedWork W1978825747 @default.
- W5130003 hasRelatedWork W2034398328 @default.
- W5130003 hasRelatedWork W2061610150 @default.
- W5130003 hasRelatedWork W2062676201 @default.
- W5130003 hasRelatedWork W2357836654 @default.
- W5130003 hasRelatedWork W2371779997 @default.
- W5130003 hasRelatedWork W2412561339 @default.
- W5130003 hasRelatedWork W2979020615 @default.
- W5130003 hasRelatedWork W5130003 @default.
- W5130003 hasRelatedWork W83711122 @default.
- W5130003 hasVolume "48" @default.
- W5130003 isParatext "false" @default.
- W5130003 isRetracted "false" @default.
- W5130003 magId "5130003" @default.
- W5130003 workType "article" @default.