Matches in SemOpenAlex for { <https://semopenalex.org/work/W51310303> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W51310303 endingPage "93" @default.
- W51310303 startingPage "89" @default.
- W51310303 abstract "Background: Elevated plasma lactate dehydrogenase (LDH) concentration may reflect hemolysis due to mechanical heart valve dysfunction. Thus, knowledge of LDH levels in patients with properly working prostheses is required. Because hemolysis parameters for the SJM Hemodynamic Plus® (HP®) and Regent® series are currently not available, the purpose of our study was to determine these data. Methods: At 12–19 months follow-up after isolated aortic valve replacement with SJM HP® or Regent® prostheses, we examined 102 patients by transthoracic echocardiography and determined plasma LDH, haptoglobin, bilirubin and hemoglobin. Results: Five patients with properly working prostheses were excluded because of increased LDH due to non-cardiac reasons. In four patients with paravalvular leakage, LDH was 244, 307, 446 and 628 U/l, respectively. In patients with properly working prostheses, LDH was 287±52 (range: 163–374) U/l for HP® (n=33) and 274±48 (151–386) U/l for Regent® valves (n=60, p=0.2). Haptoglobin was <1g/l in all patients; in 91% of HP and 75% of Regent® valves, haptoglobin was below detection limit. Bilirubin and hemoglobin as well as red blood cell count (RBC) were normal in all patients except for five patients with renal anemia, two patients with paravalvular leakage and four patients with macrocytosis due to alcohol abuse. There was no correlation between LDH and transvalvular gradient (r=−0.02) or valve size (r=0.25). Conclusions: In patients with SJM HP® or Regent® valves in aortic position, LDH values >400 U/l indicate valvular dysfunction or leakage if non-cardiac causes for hemolysis are excluded. However, paravalvular leakage can be present without substantially increased LDH. Haptoglobin has no diagnostic value as it is almost always markedly reduced. Hemolysis does not correlate with transvalvular gradient or prosthesis size." @default.
- W51310303 created "2016-06-24" @default.
- W51310303 creator A5007656686 @default.
- W51310303 creator A5015878764 @default.
- W51310303 creator A5024731098 @default.
- W51310303 creator A5058308010 @default.
- W51310303 creator A5072882723 @default.
- W51310303 creator A5080117829 @default.
- W51310303 date "2004-05-01" @default.
- W51310303 modified "2023-10-18" @default.
- W51310303 title "Hemolysis parameters of St. Jude Medical" @default.
- W51310303 cites W1966482904 @default.
- W51310303 cites W1966795238 @default.
- W51310303 cites W1973280342 @default.
- W51310303 cites W2016734504 @default.
- W51310303 cites W2024502730 @default.
- W51310303 cites W2056057364 @default.
- W51310303 cites W2071563770 @default.
- W51310303 cites W2153932243 @default.
- W51310303 cites W4240651674 @default.
- W51310303 doi "https://doi.org/10.1016/j.ijcard.2003.05.004" @default.
- W51310303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15159044" @default.
- W51310303 hasPublicationYear "2004" @default.
- W51310303 type Work @default.
- W51310303 sameAs 51310303 @default.
- W51310303 citedByCount "8" @default.
- W51310303 countsByYear W513103032013 @default.
- W51310303 countsByYear W513103032015 @default.
- W51310303 countsByYear W513103032017 @default.
- W51310303 countsByYear W513103032021 @default.
- W51310303 countsByYear W513103032023 @default.
- W51310303 crossrefType "journal-article" @default.
- W51310303 hasAuthorship W51310303A5007656686 @default.
- W51310303 hasAuthorship W51310303A5015878764 @default.
- W51310303 hasAuthorship W51310303A5024731098 @default.
- W51310303 hasAuthorship W51310303A5058308010 @default.
- W51310303 hasAuthorship W51310303A5072882723 @default.
- W51310303 hasAuthorship W51310303A5080117829 @default.
- W51310303 hasConcept C126322002 @default.
- W51310303 hasConcept C164705383 @default.
- W51310303 hasConcept C181199279 @default.
- W51310303 hasConcept C185592680 @default.
- W51310303 hasConcept C206396517 @default.
- W51310303 hasConcept C2777318727 @default.
- W51310303 hasConcept C2777513400 @default.
- W51310303 hasConcept C2778917026 @default.
- W51310303 hasConcept C2779902561 @default.
- W51310303 hasConcept C55493867 @default.
- W51310303 hasConcept C71924100 @default.
- W51310303 hasConceptScore W51310303C126322002 @default.
- W51310303 hasConceptScore W51310303C164705383 @default.
- W51310303 hasConceptScore W51310303C181199279 @default.
- W51310303 hasConceptScore W51310303C185592680 @default.
- W51310303 hasConceptScore W51310303C206396517 @default.
- W51310303 hasConceptScore W51310303C2777318727 @default.
- W51310303 hasConceptScore W51310303C2777513400 @default.
- W51310303 hasConceptScore W51310303C2778917026 @default.
- W51310303 hasConceptScore W51310303C2779902561 @default.
- W51310303 hasConceptScore W51310303C55493867 @default.
- W51310303 hasConceptScore W51310303C71924100 @default.
- W51310303 hasIssue "1" @default.
- W51310303 hasLocation W513103031 @default.
- W51310303 hasLocation W513103032 @default.
- W51310303 hasOpenAccess W51310303 @default.
- W51310303 hasPrimaryLocation W513103031 @default.
- W51310303 hasRelatedWork W1909686881 @default.
- W51310303 hasRelatedWork W2000791000 @default.
- W51310303 hasRelatedWork W2001431541 @default.
- W51310303 hasRelatedWork W2016246327 @default.
- W51310303 hasRelatedWork W2126315219 @default.
- W51310303 hasRelatedWork W2319416066 @default.
- W51310303 hasRelatedWork W2355138254 @default.
- W51310303 hasRelatedWork W2897626706 @default.
- W51310303 hasRelatedWork W2955278391 @default.
- W51310303 hasRelatedWork W2982901703 @default.
- W51310303 hasVolume "95" @default.
- W51310303 isParatext "false" @default.
- W51310303 isRetracted "false" @default.
- W51310303 magId "51310303" @default.
- W51310303 workType "article" @default.