Matches in SemOpenAlex for { <https://semopenalex.org/work/W51550641> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W51550641 endingPage "7" @default.
- W51550641 startingPage "1511" @default.
- W51550641 abstract "Arbekacin (HBK), 1-N[(S)-4-amino-2-hydroxybutyl]-3',4'-dideoxykanamycin B, showed broad antibacterial spectra against gram-positive and gram-negative bacteria including Pseudomonas aeruginosa. It was also effective against gentamycin- or tobramycin-resistant bacteria. HBK was resistant to various aminoglycoside-inactivating enzymes except for AAC (2') and AAC (6')-IV, both of which slowly inactivated it. Even at higher dosages (150 mg/kg i.m. or greater, which resulted in some deaths), HBK never decreased the pinna reflex in guinea pigs, while 150 mg/kg or more of dibekacin (DKB) or amikacin (AMK) caused loss of this reflex. HBK has less ototoxicity than do DKB and AMK. This was confirmed by histopathological examination of the inner ear. The degree of nephrotoxicity of HBK was suggested to be similar to that of DKB as judged from serum biochemical tests, urinalysis, and histopathological findings." @default.
- W51550641 created "2016-06-24" @default.
- W51550641 creator A5012378918 @default.
- W51550641 creator A5037004206 @default.
- W51550641 creator A5038390095 @default.
- W51550641 creator A5050186881 @default.
- W51550641 creator A5050678807 @default.
- W51550641 creator A5065672655 @default.
- W51550641 creator A5074766315 @default.
- W51550641 date "1986-10-01" @default.
- W51550641 modified "2023-10-16" @default.
- W51550641 title "Antibacterial activity and ototoxicity in guinea pigs, and nephrotoxicity in rats of arbekacin." @default.
- W51550641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3814212" @default.
- W51550641 hasPublicationYear "1986" @default.
- W51550641 type Work @default.
- W51550641 sameAs 51550641 @default.
- W51550641 citedByCount "6" @default.
- W51550641 countsByYear W515506412017 @default.
- W51550641 crossrefType "journal-article" @default.
- W51550641 hasAuthorship W51550641A5012378918 @default.
- W51550641 hasAuthorship W51550641A5037004206 @default.
- W51550641 hasAuthorship W51550641A5038390095 @default.
- W51550641 hasAuthorship W51550641A5050186881 @default.
- W51550641 hasAuthorship W51550641A5050678807 @default.
- W51550641 hasAuthorship W51550641A5065672655 @default.
- W51550641 hasAuthorship W51550641A5074766315 @default.
- W51550641 hasConcept C126189478 @default.
- W51550641 hasConcept C126322002 @default.
- W51550641 hasConcept C2775832221 @default.
- W51550641 hasConcept C2776694085 @default.
- W51550641 hasConcept C2777427914 @default.
- W51550641 hasConcept C2777787772 @default.
- W51550641 hasConcept C2778239845 @default.
- W51550641 hasConcept C2778534666 @default.
- W51550641 hasConcept C2778974779 @default.
- W51550641 hasConcept C2780091579 @default.
- W51550641 hasConcept C501593827 @default.
- W51550641 hasConcept C71924100 @default.
- W51550641 hasConcept C86803240 @default.
- W51550641 hasConcept C89423630 @default.
- W51550641 hasConcept C98274493 @default.
- W51550641 hasConceptScore W51550641C126189478 @default.
- W51550641 hasConceptScore W51550641C126322002 @default.
- W51550641 hasConceptScore W51550641C2775832221 @default.
- W51550641 hasConceptScore W51550641C2776694085 @default.
- W51550641 hasConceptScore W51550641C2777427914 @default.
- W51550641 hasConceptScore W51550641C2777787772 @default.
- W51550641 hasConceptScore W51550641C2778239845 @default.
- W51550641 hasConceptScore W51550641C2778534666 @default.
- W51550641 hasConceptScore W51550641C2778974779 @default.
- W51550641 hasConceptScore W51550641C2780091579 @default.
- W51550641 hasConceptScore W51550641C501593827 @default.
- W51550641 hasConceptScore W51550641C71924100 @default.
- W51550641 hasConceptScore W51550641C86803240 @default.
- W51550641 hasConceptScore W51550641C89423630 @default.
- W51550641 hasConceptScore W51550641C98274493 @default.
- W51550641 hasIssue "10" @default.
- W51550641 hasLocation W515506411 @default.
- W51550641 hasOpenAccess W51550641 @default.
- W51550641 hasPrimaryLocation W515506411 @default.
- W51550641 hasRelatedWork W1602548439 @default.
- W51550641 hasRelatedWork W2002751898 @default.
- W51550641 hasRelatedWork W2026055258 @default.
- W51550641 hasRelatedWork W2085721202 @default.
- W51550641 hasRelatedWork W2169800903 @default.
- W51550641 hasRelatedWork W2405713811 @default.
- W51550641 hasRelatedWork W2423258035 @default.
- W51550641 hasRelatedWork W2912951213 @default.
- W51550641 hasRelatedWork W4249693897 @default.
- W51550641 hasRelatedWork W51550641 @default.
- W51550641 hasVolume "36" @default.
- W51550641 isParatext "false" @default.
- W51550641 isRetracted "false" @default.
- W51550641 magId "51550641" @default.
- W51550641 workType "article" @default.