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- W515701 abstract "Newcastle disease virus (NDV) can be isolated from a wide variety of different avian species. Differences in virus pathogenicity have been observed which depend on the host infected as well as on the virus strain involved. Chickens seem to be the most susceptible species. Ducks and geese, on the other hand, are reported to be refractory even to the most pathogenic viruses for chickens (27). There is evidence that adaptation of a particular NDV strain to a novel host may affect pathogenicity. Thus, Alexander and Parsons (1) reported that NDV isolates from pigeons required several passages in chickens, before their potential pathogenicity became manifest in this species. Although the reason for this host specificity of NDV is not known, such observations are of epidemiological significance. They explain how potentially pathogenic virus strains can be generated and maintained in a particular species without harm. This pathogenic potential could then become fully manifest when a different species of highly susceptible birds, such as chicken, is exposed to these viruses." @default.
- W515701 created "2016-06-24" @default.
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- W515701 date "1988-01-01" @default.
- W515701 modified "2023-09-26" @default.
- W515701 title "Molecular Basis of Infectivity and Pathogenicity of Newcastle Disease Virus" @default.
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- W515701 doi "https://doi.org/10.1007/978-1-4613-1759-3_6" @default.
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