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• W5196601 abstract "Adenocarcinoma of the prostate is the most common malignancy and the second leading cause of cancer death in North American men. There is a consensus among the urological community that early detection and treatment of clinically localized prostate cancer (Pca) in men with a 10-yr life expectancy are beneficial. Recent statistics from the American Cancer Society demonstrate that the death rate from Pca is declining despite the aging of the male population, presumably owing to prostate-specific-antigen- (PSA) based screening (1). Radical prostatectomy (RP) and radiation therapy (RT) are the most common forms of definitive treatment for clinically localized Pca. Cryosurgery is utilized as an alternative therapy in poor surgical candidates or when RT is contraindicated. The incidence of disease recurrence following initial treatment depends on many parameters, including pretreatment serum PSA levels, Gleason score, and clinical-pathological stage (2–4). Treatment outcomes for the various therapies available for Pca are variable with 3- to 5-yr rates of biochemical disease control ranging from 20 to 92% for RP and 8 to 90% for patients treated with RT (Table 1) (5–10). The incidence of histologically persistent Pca following cryotherapy or RT has been reported to be at least 20% (5,11–13)." @default.
• W5196601 created "2016-06-24" @default.
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• W5196601 date "2000-01-01" @default.
• W5196601 modified "2023-09-26" @default.
• W5196601 title "Management of Recurrent Disease After Definitive Therapy" @default.
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• W5196601 doi "https://doi.org/10.1007/978-1-59259-714-7_14" @default.
• W5196601 hasPublicationYear "2000" @default.
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