FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W52066678> ?p ?o ?g. }

• W52066678 endingPage "244" @default.
• W52066678 startingPage "237" @default.
• W52066678 abstract "A lipolysis model was characterised and evaluated by investigating the composition of the aqueous phase and the concentration of probucol and danazol in the aqueous phase. Effects of bile salt levels at 5, 10, 20, and 30 mM were investigated. Samples were taken at 0%, 50%, 75% and 95% hydrolysis of the triglycerides, and the aqueous phases were isolated by ultra-centrifugation, whereby the concentrations of bile salts, fatty acids, mono-, di-, triglycerides, and drug substances were measured. At high Ca(2+)-concentrations, bile salts were believed to precipitate with Ca(2+). The concentration of lipolytic products (fatty acids + monoglycerides) was dependent on the bile salt concentration. The ratio between lipolytic product and bile salts was 1.55+/-0.09 (S.D.). This ratio is equivalent to mixed bile salt micelles and vesicles in equilibrium. The aqueous solubility of probucol and danazol was increased in the presence of bile salts. The concentration of danazol in the aqueous phase was dependent on the solubilisation capacity of the aqueous phase. In the case of probucol, the concentration in the aqueous phase was dependent on the partition of probucol between the aqueous phase and the remaining triglyceride phase. This difference between danazol and probucol was attributed to the effect of different lipophilicity." @default.
• W52066678 created "2016-06-24" @default.
• W52066678 creator A5024434752 @default.
• W52066678 creator A5064072022 @default.
• W52066678 creator A5080165609 @default.
• W52066678 creator A5091191585 @default.
• W52066678 date "2001-10-01" @default.
• W52066678 modified "2023-10-16" @default.
• W52066678 title "A dynamic in vitro lipolysis model" @default.
• W52066678 cites W1490573286 @default.
• W52066678 cites W1498305210 @default.
• W52066678 cites W1593290141 @default.
• W52066678 cites W1751441418 @default.
• W52066678 cites W1964172500 @default.
• W52066678 cites W1969724933 @default.
• W52066678 cites W1997764055 @default.
• W52066678 cites W2029554708 @default.
• W52066678 cites W2031104654 @default.
• W52066678 cites W2044250881 @default.
• W52066678 cites W2070794837 @default.
• W52066678 cites W2082502730 @default.
• W52066678 cites W2083124588 @default.
• W52066678 cites W2083214254 @default.
• W52066678 cites W2133132084 @default.
• W52066678 cites W2135239085 @default.
• W52066678 cites W2152311269 @default.
• W52066678 cites W2206309247 @default.
• W52066678 cites W25021539 @default.
• W52066678 doi "https://doi.org/10.1016/s0928-0987(01)00182-8" @default.
• W52066678 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11576829" @default.
• W52066678 hasPublicationYear "2001" @default.
• W52066678 type Work @default.
• W52066678 sameAs 52066678 @default.
• W52066678 citedByCount "180" @default.
• W52066678 countsByYear W520666782012 @default.
• W52066678 countsByYear W520666782013 @default.
• W52066678 countsByYear W520666782014 @default.
• W52066678 countsByYear W520666782015 @default.
• W52066678 countsByYear W520666782016 @default.
• W52066678 countsByYear W520666782017 @default.
• W52066678 countsByYear W520666782018 @default.
• W52066678 countsByYear W520666782019 @default.
• W52066678 countsByYear W520666782020 @default.
• W52066678 countsByYear W520666782021 @default.
• W52066678 countsByYear W520666782022 @default.
• W52066678 countsByYear W520666782023 @default.
• W52066678 crossrefType "journal-article" @default.
• W52066678 hasAuthorship W52066678A5024434752 @default.
• W52066678 hasAuthorship W52066678A5064072022 @default.
• W52066678 hasAuthorship W52066678A5080165609 @default.
• W52066678 hasAuthorship W52066678A5091191585 @default.
• W52066678 hasConcept C11268172 @default.
• W52066678 hasConcept C126322002 @default.
• W52066678 hasConcept C140985366 @default.
• W52066678 hasConcept C149556010 @default.
• W52066678 hasConcept C155574463 @default.
• W52066678 hasConcept C171089720 @default.
• W52066678 hasConcept C178790620 @default.
• W52066678 hasConcept C184651966 @default.
• W52066678 hasConcept C185592680 @default.
• W52066678 hasConcept C192552737 @default.
• W52066678 hasConcept C201399114 @default.
• W52066678 hasConcept C2776167589 @default.
• W52066678 hasConcept C2777416354 @default.
• W52066678 hasConcept C2778163477 @default.
• W52066678 hasConcept C2779522080 @default.
• W52066678 hasConcept C2779564620 @default.
• W52066678 hasConcept C43617362 @default.
• W52066678 hasConcept C55493867 @default.
• W52066678 hasConcept C71924100 @default.
• W52066678 hasConcept C94412978 @default.
• W52066678 hasConceptScore W52066678C11268172 @default.
• W52066678 hasConceptScore W52066678C126322002 @default.
• W52066678 hasConceptScore W52066678C140985366 @default.
• W52066678 hasConceptScore W52066678C149556010 @default.
• W52066678 hasConceptScore W52066678C155574463 @default.
• W52066678 hasConceptScore W52066678C171089720 @default.
• W52066678 hasConceptScore W52066678C178790620 @default.
• W52066678 hasConceptScore W52066678C184651966 @default.
• W52066678 hasConceptScore W52066678C185592680 @default.
• W52066678 hasConceptScore W52066678C192552737 @default.
• W52066678 hasConceptScore W52066678C201399114 @default.
• W52066678 hasConceptScore W52066678C2776167589 @default.
• W52066678 hasConceptScore W52066678C2777416354 @default.
• W52066678 hasConceptScore W52066678C2778163477 @default.
• W52066678 hasConceptScore W52066678C2779522080 @default.
• W52066678 hasConceptScore W52066678C2779564620 @default.
• W52066678 hasConceptScore W52066678C43617362 @default.
• W52066678 hasConceptScore W52066678C55493867 @default.
• W52066678 hasConceptScore W52066678C71924100 @default.
• W52066678 hasConceptScore W52066678C94412978 @default.
• W52066678 hasIssue "3" @default.
• W52066678 hasLocation W520666781 @default.
• W52066678 hasLocation W520666782 @default.
• W52066678 hasOpenAccess W52066678 @default.
• W52066678 hasPrimaryLocation W520666781 @default.
• W52066678 hasRelatedWork W198492043 @default.
• W52066678 hasRelatedWork W1989593392 @default.

• next