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- W5214059 abstract "Efficacy and safety of moxifloxacin in the emergency setting M oxifloxacin is a 4 th -generation fluoroquinolone with recognised efficacy in airway infections in the emergency setting. At present, its wide spectrum that encompasses Gram-positive, Gram-negative and atypical bacteria, its greater activity against key pathogens, its almost nonexistent resistances and its excellent pharmacodynamic and pharmacokinetic features render it into the “reference fluoroquinolone”, with guaranteed success in the empirical and directed management in the emergency setting. The present review shall address the differences to other antimicrobials, mainly quinolones, in order to update the true role of moxifloxacin in airway infections. In vitro evidence and in vivo practical experience demonstrate its efficacy in achieving clinical cure and bacterial eradication, in increasing the period between COPD exacerbations, its “lack of resistances” and but slight ability to induce them, and its excellent dosage regime and tolerance, which have led a number of scientific societies to recommend moxifloxacin as the reference drug in the management of airway conditions, both in at-home and in admission therapy." @default.
- W5214059 created "2016-06-24" @default.
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- W5214059 date "2006-01-01" @default.
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- W5214059 title "Eficacia y seguridad de moxifloxacino en Urgencias" @default.
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