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- W52563736 abstract "68 patients (from newborns to 18 years of age) were studied prospectively for adverse effects associated with methicillin, nafcillin and oxacillin. Hematologic, liver and renal function tests were monitored before and during therapy. 3 of 28 patients receiving methicillin developed eosinophilia within 5-8 days. Of 32 patients on nafcillin, 2 had neutropenia within 4-13 days, 3 had eosinophilia within 1-4 days and 1 elevated liver enzymes on day 3. Of 8 patients receiving oxacillin, 1 developed neutropenia on day 11 and another showed elevation of liver enzymes on day 15. All abnormalities were reversible with the discontinuation of therapy. Appropriate laboratory tests should be monitored to detect an occurrence of adverse reaction to methicillin, nafcillin and oxacillin." @default.
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- W52563736 date "1982-01-01" @default.
- W52563736 modified "2023-10-11" @default.
- W52563736 title "Adverse Effects of Methicillin, Nafcillin and Oxacillin in Pediatric Patients" @default.
- W52563736 doi "https://doi.org/10.1159/000457400" @default.
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