FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W52810994> ?p ?o ?g. }

• W52810994 endingPage "9" @default.
• W52810994 startingPage "495" @default.
• W52810994 abstract "Osteoarthritis (OA) is the most common form of arthritis seen clinically. Current treatments for OA are limited to decreasing associated pain, maintaining or improving joint function, and minimizing disability. However, these treatments have no effect on the regeneration of hyaline cartilage. Since mesenchymal stem cells (MSCs) have been described as promising cell sources for cartilage repair, the present study was designed to examine whether intra-articular injection of scaffold-free adipose-derived stem cells (ASCs) obtained from subcutaneous adipose tissue could restore the matrix of arthritic knee joints in mature animals.OA was induced in adult white New Zealand rabbits by unilateral anterior cruciate ligament transection (ACLT); the contralateral knee was considered the sham-operated group. At 12 weeks following surgery, the ASCs treated group was injected intra-articularly with a single dose of 1 × 10(6) cells suspended in 1 mL of medium. The control group received 1 mL of medium without cells and the sham-operated group received no treatment. All rabbits were sacrificed at 16 and 20 weeks after surgery. OA progression was evaluated radiologically, grossly, and histologically using hematoxylin and eosin, Safranin-O, and toluidine blue staining.At 12 weeks after surgery all knees subjected to ACLT showed radiological signs of OA. The findings showed significant differences in the quality of cartilage between ASCs-injected group compared to control group, particularly at 20 weeks after surgery.This study suggests that ASCs obtained from subcutaneous adipose tissue could be a viable approach for treating OA." @default.
• W52810994 created "2016-06-24" @default.
• W52810994 creator A5035438703 @default.
• W52810994 creator A5048920480 @default.
• W52810994 creator A5055398153 @default.
• W52810994 creator A5071827805 @default.
• W52810994 creator A5078834482 @default.
• W52810994 creator A5080800917 @default.
• W52810994 creator A5087998377 @default.
• W52810994 date "2012-08-01" @default.
• W52810994 modified "2023-10-16" @default.
• W52810994 title "Scaffold-free adipose-derived stem cells (ASCs) improve experimentally induced osteoarthritis in rabbits." @default.
• W52810994 cites W1522229466 @default.
• W52810994 cites W1763533364 @default.
• W52810994 cites W194903029 @default.
• W52810994 cites W1971051369 @default.
• W52810994 cites W1980399656 @default.
• W52810994 cites W1981567453 @default.
• W52810994 cites W1983085571 @default.
• W52810994 cites W1992786647 @default.
• W52810994 cites W1993326869 @default.
• W52810994 cites W2004015037 @default.
• W52810994 cites W2007541978 @default.
• W52810994 cites W2019755752 @default.
• W52810994 cites W2035040282 @default.
• W52810994 cites W2052142623 @default.
• W52810994 cites W2053270805 @default.
• W52810994 cites W2053376015 @default.
• W52810994 cites W2069810199 @default.
• W52810994 cites W2070435400 @default.
• W52810994 cites W2083859757 @default.
• W52810994 cites W2087230484 @default.
• W52810994 cites W2089575429 @default.
• W52810994 cites W2102421439 @default.
• W52810994 cites W2107503723 @default.
• W52810994 cites W2111960560 @default.
• W52810994 cites W2116000120 @default.
• W52810994 cites W2116500923 @default.
• W52810994 cites W2132865989 @default.
• W52810994 cites W2149996379 @default.
• W52810994 cites W2155521015 @default.
• W52810994 cites W2163219293 @default.
• W52810994 cites W2180059107 @default.
• W52810994 cites W2262845527 @default.
• W52810994 cites W2299160010 @default.
• W52810994 cites W2407666413 @default.
• W52810994 cites W2058514588 @default.
• W52810994 cites W2187170218 @default.
• W52810994 cites W44674334 @default.
• W52810994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22827787" @default.
• W52810994 hasPublicationYear "2012" @default.
• W52810994 type Work @default.
• W52810994 sameAs 52810994 @default.
• W52810994 citedByCount "28" @default.
• W52810994 countsByYear W528109942013 @default.
• W52810994 countsByYear W528109942014 @default.
• W52810994 countsByYear W528109942015 @default.
• W52810994 countsByYear W528109942016 @default.
• W52810994 countsByYear W528109942017 @default.
• W52810994 countsByYear W528109942018 @default.
• W52810994 countsByYear W528109942019 @default.
• W52810994 countsByYear W528109942021 @default.
• W52810994 countsByYear W528109942022 @default.
• W52810994 countsByYear W528109942023 @default.
• W52810994 crossrefType "journal-article" @default.
• W52810994 hasAuthorship W52810994A5035438703 @default.
• W52810994 hasAuthorship W52810994A5048920480 @default.
• W52810994 hasAuthorship W52810994A5055398153 @default.
• W52810994 hasAuthorship W52810994A5071827805 @default.
• W52810994 hasAuthorship W52810994A5078834482 @default.
• W52810994 hasAuthorship W52810994A5080800917 @default.
• W52810994 hasAuthorship W52810994A5087998377 @default.
• W52810994 hasConcept C105702510 @default.
• W52810994 hasConcept C125473707 @default.
• W52810994 hasConcept C126322002 @default.
• W52810994 hasConcept C141071460 @default.
• W52810994 hasConcept C142724271 @default.
• W52810994 hasConcept C171056886 @default.
• W52810994 hasConcept C171089720 @default.
• W52810994 hasConcept C198826908 @default.
• W52810994 hasConcept C204787440 @default.
• W52810994 hasConcept C2776164576 @default.
• W52810994 hasConcept C2777077863 @default.
• W52810994 hasConcept C2780024818 @default.
• W52810994 hasConcept C2780550940 @default.
• W52810994 hasConcept C28328180 @default.
• W52810994 hasConcept C3020332539 @default.
• W52810994 hasConcept C54355233 @default.
• W52810994 hasConcept C71924100 @default.
• W52810994 hasConcept C74864618 @default.
• W52810994 hasConcept C86803240 @default.
• W52810994 hasConcept C95444343 @default.
• W52810994 hasConceptScore W52810994C105702510 @default.
• W52810994 hasConceptScore W52810994C125473707 @default.
• W52810994 hasConceptScore W52810994C126322002 @default.
• W52810994 hasConceptScore W52810994C141071460 @default.
• W52810994 hasConceptScore W52810994C142724271 @default.
• W52810994 hasConceptScore W52810994C171056886 @default.

• next