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- W53082289 abstract "Progress in prevention of any disease is enhanced by the identification of a group of individuals who are at increased risk to develop the disease. The ability to detect families with evident predisposition to malignancy provides a unique opportunity to study high-risk groups. Recent studies of the p53 gene have suggested that heritable mutations in this gene may predispose affected individuals to the development of a wide variety of tumors. In this article, evidence for the involvement of p53 in inheritable cancers is assessed, and the implications for future studies are discussed." @default.
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- W53082289 date "1992-01-01" @default.
- W53082289 modified "2023-09-23" @default.
- W53082289 title "Identification of cancer-prone individuals: p53 and family cancer syndromes." @default.
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