Matches in SemOpenAlex for { <https://semopenalex.org/work/W53092918> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W53092918 endingPage "8" @default.
- W53092918 startingPage "165" @default.
- W53092918 abstract "Anticipation is a phenomenon in which successive generations within a family experience an earlier age of onset and a more severe form of a given illness. It has been observed in various neurological and psychiatric conditions, including bipolar disorder. The molecular basis of anticipation involves trinucleotide repeat expansions in genes, but this has not been conclusively demonstrated in bipolar disorder. The histories of 3 father-son pairs are presented. In each pair, the son presented with an early-onset bipolar disorder, and the father developed severe depression after the age of 50 years. No female relatives were affected. The implications of these observations are discussed. Genetic, epigenetic, and environmental mechanisms that may have contributed to this phenomenon are briefly described. The study of such patients may throw light on the extended phenotype of mood disorders, as well as the genetic and epigenetic mechanisms involved in the phenomena of anticipation and phenotypic variation." @default.
- W53092918 created "2016-06-24" @default.
- W53092918 creator A5072855984 @default.
- W53092918 date "2014-12-01" @default.
- W53092918 modified "2023-09-23" @default.
- W53092918 title "Anticipation with phenotypic variation in three father-son pairs with affective disorder: a case series." @default.
- W53092918 cites W1491248060 @default.
- W53092918 cites W1511881539 @default.
- W53092918 cites W1552920185 @default.
- W53092918 cites W1560231616 @default.
- W53092918 cites W1576118007 @default.
- W53092918 cites W1790953093 @default.
- W53092918 cites W1964025163 @default.
- W53092918 cites W1984744073 @default.
- W53092918 cites W2022592378 @default.
- W53092918 cites W2030515753 @default.
- W53092918 cites W2034761715 @default.
- W53092918 cites W2039440352 @default.
- W53092918 cites W2046562432 @default.
- W53092918 cites W2064554173 @default.
- W53092918 cites W2064931619 @default.
- W53092918 cites W2107152097 @default.
- W53092918 cites W2162936944 @default.
- W53092918 cites W2168648494 @default.
- W53092918 cites W2415896524 @default.
- W53092918 cites W94675760 @default.
- W53092918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25482836" @default.
- W53092918 hasPublicationYear "2014" @default.
- W53092918 type Work @default.
- W53092918 sameAs 53092918 @default.
- W53092918 citedByCount "0" @default.
- W53092918 crossrefType "journal-article" @default.
- W53092918 hasAuthorship W53092918A5072855984 @default.
- W53092918 hasConcept C104317684 @default.
- W53092918 hasConcept C118552586 @default.
- W53092918 hasConcept C126322002 @default.
- W53092918 hasConcept C127716648 @default.
- W53092918 hasConcept C138496976 @default.
- W53092918 hasConcept C154945302 @default.
- W53092918 hasConcept C15744967 @default.
- W53092918 hasConcept C176777502 @default.
- W53092918 hasConcept C2776174506 @default.
- W53092918 hasConcept C2777134132 @default.
- W53092918 hasConcept C2777767895 @default.
- W53092918 hasConcept C2779134260 @default.
- W53092918 hasConcept C2780733359 @default.
- W53092918 hasConcept C41008148 @default.
- W53092918 hasConcept C41091548 @default.
- W53092918 hasConcept C54355233 @default.
- W53092918 hasConcept C558461103 @default.
- W53092918 hasConcept C71924100 @default.
- W53092918 hasConcept C86803240 @default.
- W53092918 hasConceptScore W53092918C104317684 @default.
- W53092918 hasConceptScore W53092918C118552586 @default.
- W53092918 hasConceptScore W53092918C126322002 @default.
- W53092918 hasConceptScore W53092918C127716648 @default.
- W53092918 hasConceptScore W53092918C138496976 @default.
- W53092918 hasConceptScore W53092918C154945302 @default.
- W53092918 hasConceptScore W53092918C15744967 @default.
- W53092918 hasConceptScore W53092918C176777502 @default.
- W53092918 hasConceptScore W53092918C2776174506 @default.
- W53092918 hasConceptScore W53092918C2777134132 @default.
- W53092918 hasConceptScore W53092918C2777767895 @default.
- W53092918 hasConceptScore W53092918C2779134260 @default.
- W53092918 hasConceptScore W53092918C2780733359 @default.
- W53092918 hasConceptScore W53092918C41008148 @default.
- W53092918 hasConceptScore W53092918C41091548 @default.
- W53092918 hasConceptScore W53092918C54355233 @default.
- W53092918 hasConceptScore W53092918C558461103 @default.
- W53092918 hasConceptScore W53092918C71924100 @default.
- W53092918 hasConceptScore W53092918C86803240 @default.
- W53092918 hasIssue "4" @default.
- W53092918 hasLocation W530929181 @default.
- W53092918 hasOpenAccess W53092918 @default.
- W53092918 hasPrimaryLocation W530929181 @default.
- W53092918 hasRelatedWork W1973495558 @default.
- W53092918 hasRelatedWork W2178355872 @default.
- W53092918 hasRelatedWork W2338062043 @default.
- W53092918 hasRelatedWork W2416363906 @default.
- W53092918 hasRelatedWork W2804820656 @default.
- W53092918 hasRelatedWork W3023925757 @default.
- W53092918 hasRelatedWork W3128235182 @default.
- W53092918 hasRelatedWork W3184164767 @default.
- W53092918 hasRelatedWork W53092918 @default.
- W53092918 hasRelatedWork W64784700 @default.
- W53092918 hasVolume "24" @default.
- W53092918 isParatext "false" @default.
- W53092918 isRetracted "false" @default.
- W53092918 magId "53092918" @default.
- W53092918 workType "article" @default.