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- W53148932 abstract "The vascular effects of gramine on resistance vessels were evaluated, in particular as regards the 5-hydroxytryptamine (5-HT) system. We compared the action of gramine with that of ketanserin, a 5-HT2A antagonist; both compounds induced concentration-dependent relaxation in precontracted arterial rings. Also, the 5-HT concentration-effect curve shifted to the right in the presence of gramine, like ketanserin. These results suggest that gramine is a vasorelaxing agent acting mainly by antagonism at 5-HT2A receptors." @default.
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- W53148932 date "2004-04-01" @default.
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- W53148932 title "Gramine: A Vasorelaxing Alkaloid Acting on 5-HT<sub>2A</sub>Receptors" @default.
- W53148932 doi "https://doi.org/10.1055/s-2004-818953" @default.
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