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• W53244928 abstract "A 40-year-old Hispanic man without conventional risk factors for coronary artery disease presented with an inferior ST-elevation myocardial infarction and underwent emergent intervention with a drug-eluting stent deployed to his occluded mid right coronary artery (RCA). Four months later, he returned with a large, painful, right femoral artery pseudoaneurysm (Fig. 1) at the site of the collagen-plug vascular closure device that had been used during this cardiac catheterization; the pseudoaneurysm required surgical intervention. During this hospitalization, the patient was noted to have low-grade fevers and oral ulcers, which he had also experienced intermittently in the past. An extensive infectious-disease and rheumatologic evaluation revealed only an elevated erythrocyte sedimentation rate and C-reactive protein level. The possibility of Behcet syndrome was considered but was deemed unlikely, due to the patient's non-European descent and the lack of genital and ocular involvement. A presumptive diagnosis of atypical recurrent aphthous stomatitis was made based on the absence of lymphadenopathy.Fig. 1 Ultrasonographic image of the right femoral artery shows a large pseudoaneurysm (arrow).One month later (5 months after his initial myocardial infarction), the patient presented again—this time with atypical chest pain. Echocardiography showed a large inferobasilar ventricular pseudoaneurysm (Fig. 2). Chest radiography showed nonspecific cardiomegaly. Cardiac magnetic resonance imaging, performed in preparation for surgical pseudoaneurysmectomy, further delineated the inferobasilar ventricular pseudoaneurysm in the setting of prior inferior-wall myocardial infarction (Fig. 3). Coronary angiography revealed a large RCA pseudoaneurysm and thrombotic occlusion of the RCA stent (Fig. 4). The patient underwent successful surgical repair of the ventricular pseudoaneurysm, with resection and ligation of the RCA pseudoaneurysm. Histopathologic analysis of the RCA pseudoaneurysm suggested Behcet syndrome (Fig. 5). More than a year later, he was doing well on methotrexate and infliximab therapy for Behcet syndrome.Fig. 2 Two-chamber echocardiographic views show the large inferobasilar pseudoaneurysm with a narrow neck pathognomonic for a pseudoaneurysm: A) without contrast, and B) contrast-enhanced.Fig. 3 Corresponding cardiac magnetic resonance imaging 2-chamber views show the inferobasilar ventricular pseudoaneurysm and a moderate anterior pericardial effusion: A) cine image, and B) delayed-enhancement image after gadolinium infusion, which shows ...Fig. 4 Coronary angiograms of the right coronary artery A) at the time of acute inferior ST-elevation myocardial infarction, B) immediately after percutaneous intervention with a drug-eluting stent, and C) before surgical repair of the ventricular pseudoaneurysm, ...Fig. 5 A) Scanning electron microscopic view of the right coronary artery (RCA) stent. B) Hematoxylin & eosin stain (orig. ×40) of RCA pseudoaneurysm, in which the asterisk (*) shows stent struts with overlying thrombus. C) Photomicrograph ..." @default.
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• W53244928 date "2009-01-01" @default.
• W53244928 modified "2023-09-23" @default.
• W53244928 title "Cardiovascular complications in Behçet syndrome: acute myocardial infarction with late stent thrombosis and coronary, ventricular, and femoral pseudoaneurysms." @default.
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