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- W53419019 endingPage "54" @default.
- W53419019 startingPage "54" @default.
- W53419019 abstract "In recent decades, the prominent role of endoscopy in the management of ulcerative colitis (UC) has been translated into the concept of mucosal healing (MH) as a fundamental therapeutic end-point. This is partially the consequence of growing evidence of a positive prognostic role of MH on the disease course and partially due to market cues indicating a higher rate of MH in patients treated by novel potent biologic agents. The aim of the present review is to clarify the current knowledge of MH in UC, analyzing the definition, the putative prognostic role and the association of MH with the current drugs used to treat UC patients. Because solid data about the management of UC patients based solely on the healing of the mucosa are not yet available, a tailored approach for individual patients thatconsiders the natural history of UC and the presence of prognostic indicators of aggressive disease is desirable. Consequently, unnecessary examinations and treatment would be avoided and restricted to UC patients who require the maximum amount of effort to affect the disease course in the short and long term." @default.
- W53419019 created "2016-06-24" @default.
- W53419019 creator A5018969457 @default.
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- W53419019 creator A5049004748 @default.
- W53419019 creator A5070864397 @default.
- W53419019 creator A5089237045 @default.
- W53419019 date "2014-01-01" @default.
- W53419019 modified "2023-09-27" @default.
- W53419019 title "“Mucosal healing” in ulcerative colitis: Between clinical evidence and market suggestion" @default.
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- W53419019 doi "https://doi.org/10.4291/wjgp.v5.i2.54" @default.
- W53419019 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4025073" @default.
- W53419019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24891976" @default.
- W53419019 hasPublicationYear "2014" @default.
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