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- W53637711 abstract "2′-Deoxy-5-fluoro-5′-O-(tetrahydro-2H-1”,3”,2”-oxaphosphorine 2”-oxide-2”-yl)uridine (11) has been synthesised by two routes from 2′-deoxy-5-fluorouridine. The product, after metabolic hydroxylation, is a potential source of 2′-deoxy-5-fluorouridine 5′-phosphate, the active metabolite of the anticancer drug 2′-deoxy-5-fluorouridine and has been tested in vivo against Sarcoma S-180 in mice." @default.
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- W53637711 date "1980-01-01" @default.
- W53637711 modified "2023-09-27" @default.
- W53637711 title "THE SYNTHESIS OF A POTENTIALLY METABOLICALLY-LABILE DERIVATIVE OF 2′-DEOXY-5-FLUOROURIDINE 5′-PHOSPHATE" @default.
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- W53637711 doi "https://doi.org/10.1016/b978-0-08-023969-9.50009-3" @default.
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