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- W5393456 abstract "Healthcare-associated infections (HCAI) are a result of direct medical care; treatment in hospitals, care homes and the patient’s own residence; and contact with a healthcare setting. The implication of them include prolonged patient stay, reductions in bed availability and increased diagnostic testing and infection control procedures. Infections can be caused by indwelling medical devices, including ventilators, catheters, shunts and endoscopes; they can also occur following surgical procedures through contact with contaminated surfaces or air-borne fungal spores. The most common infections are ventilator-associated pneumonia, central-line-associated septicaemia , catheter-associated UTIs, C. difficile and surgical site wound infection. Several species of bacteria and fungi cause HCAI; the most widely publicised is the hospital ‘superbug’—MRSA, a common cause of bacteraemia and septicaemia . Antibiotic-resistant strains are difficult to defeat because of the lack of treatment options and because bacteria and fungi are known to colonise surgical and chronic wounds and grow as a biofilm. This chapter discusses biofilm-related HCAI and their detection, evidence of biofilm formation, host responses to microbial biofilms and preventative anti-biofilm strategies." @default.
- W5393456 created "2016-06-24" @default.
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- W5393456 date "2014-01-01" @default.
- W5393456 modified "2023-09-27" @default.
- W5393456 title "Healthcare-Associated Infections and Biofilms" @default.
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- W5393456 doi "https://doi.org/10.1016/b978-0-12-397043-5.00010-4" @default.
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