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- W54024103 abstract "Hyun-Woo Kim․Young-Joon Jung․Dong-Gye Lee․Sang-Geun Han․Eui-Su ChoungHee-Taek Kim․Se-Chan Kang Objectives : To investigate the effects of DL-HGF to hair growth activity in mouse, various kinds of ethosome and liposome formulations entrapped DL-HGF were produc ed and this study was carried out. Methods : The B16/BL6 mice were classified into five groups: vehicle c ontrol (Con) group, Et-1-applied group, Et-2-applied group, LP-1-applied group, LP-2-applied group. Active hair growth (anagen) was induced in the back skin by application of a wax–osin mixture with subsequent depilation and the activity of hai r growth was measured by macroscopic observation and histology. Results : In vehicle control group, there was no hair growth activity during experiment period. In Et-1-applied group, the rate of hair growth was about 100%, LP- 1-applied group and Et-2-applied group showed 70-80% and 40-50% of hair growth rates, respectively. The rate of hair growth of LP-2-applied group was lower than other applied groups (20-30%). In H/E stai ning, Numerous hair folicles and hair shafts were observed in Et-1-applied group and other groups showed lower level of hair folicles and hair shafts formation than Et-1-applied group. Conclusion : Et-1 formulation showed highest hair growth activity than ot her ethosome and liposome formulations entrapped DL-HGF.Key words : Hair growth, DL-HGF, Ethosome, Liposome" @default.
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- W54024103 date "2009-01-01" @default.
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- W54024103 title "The Effects of Ethosome and Liposome Formulation Entrapped DL-HGF to Hair Growth Activity in Animal Model" @default.
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