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- W54326455 abstract "We classified the degree of pineal calcification (DOC) into seven groups using cranial Computer Tomography (cCT) and then correlated pineal DOC to chronic subjective sleep-related disturbances as measured by a sleep questionnaire in 36 patients. Analysed by logistic regression models, age and sex were not, but higher pineal DOC was significantly associated with the presence of daytime tiredness (OR=4.15, 95% CI: 1.63, 10.54) and sleep disturbance (OR=1.74, 95% CI: 1.10, 2.74). This study provides initial confirmation of the hypothesis that the increasing degree of pineal calcification (DOC) might indicate a decrease of melatonin production, which consecutively might lead to a disturbed circadian rhythmicity in the sleep-wake cycle, with the principal symptom being daytime tiredness." @default.
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- W54326455 date "1991-07-01" @default.
- W54326455 modified "2023-09-23" @default.
- W54326455 title "Pineal calcification in schizophrenia" @default.
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- W54326455 doi "https://doi.org/10.1016/0920-9964(91)90057-x" @default.
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