Matches in SemOpenAlex for { <https://semopenalex.org/work/W54408052> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W54408052 abstract "The vast ocean has the reputation of having the greatest biodiversity. Therefore, represents an enormous resource for the discovery of chemotherapeutic agents. This particular investigation delves upon the study of bioactive compound from two marine sponges from coastal waters of Sabah, Amphimedon sp. and Xestospongia sp. and the most active sponge was then investigated for its relationship with its inherently available culturable bacteria in an effort to confirm the identity of the bioactive compound producer. All fractions except for fraction 1 and fraction 6 from the hexane crude extract from Amphimedon sp. showed antibacterial activity against 5 strains of marine environmental bacteria while all fractions except for fraction 1 from the 90% methanol crude extract showed antibacterial activity against 5 strains of marine environmental bacteria. Amphimedon sp. produced potent sterol as its bioactive compound, while Xestosponge sp produced aaptamine. Their identities were identified based on extensive Hl-NMR and MS data. Spongebacteria relationship was carried out by isolating culturable bacteria from sponge tissues, and a total of 40 strains of bacteria were isolated from Amphimedon sp. but only one strain (AA1) was found to have bioactive activity. 16S rRNA regions of AA1 were amplified using forward primer 27F (GAGTTTGATCCTGGCTCAG) while the reverse primer was JR1R (GACTACCAGGGTABCTAATC) and was compared with the top three matches provided by NCBI GenBank. Strain AA1 was found to be pro Bacillus sp. with 99% confidence and with e-value of zero. A mixture of fatty acids were isolated as active metabolite from AA1 and upon gas chromatography (GC) analysis and antibacterial assay with corresponding commercial fatty acids. It was confirmed that hexadecenoate was the active compound in AA1. In conclusion, culturable bacteria were not responsible for the production of active compounds in Amphimedon sp." @default.
- W54408052 created "2016-06-24" @default.
- W54408052 creator A5072483585 @default.
- W54408052 date "2010-01-01" @default.
- W54408052 modified "2023-09-27" @default.
- W54408052 title "Bacteria - sponge interaction: Existence of possible chemical correlation" @default.
- W54408052 hasPublicationYear "2010" @default.
- W54408052 type Work @default.
- W54408052 sameAs 54408052 @default.
- W54408052 citedByCount "0" @default.
- W54408052 crossrefType "dissertation" @default.
- W54408052 hasAuthorship W54408052A5072483585 @default.
- W54408052 hasConcept C104317684 @default.
- W54408052 hasConcept C105702510 @default.
- W54408052 hasConcept C153568844 @default.
- W54408052 hasConcept C185592680 @default.
- W54408052 hasConcept C2778022156 @default.
- W54408052 hasConcept C2778849931 @default.
- W54408052 hasConcept C2780104969 @default.
- W54408052 hasConcept C31903555 @default.
- W54408052 hasConcept C42062724 @default.
- W54408052 hasConcept C523546767 @default.
- W54408052 hasConcept C54355233 @default.
- W54408052 hasConcept C55493867 @default.
- W54408052 hasConcept C59822182 @default.
- W54408052 hasConcept C79029880 @default.
- W54408052 hasConcept C86803240 @default.
- W54408052 hasConcept C89423630 @default.
- W54408052 hasConceptScore W54408052C104317684 @default.
- W54408052 hasConceptScore W54408052C105702510 @default.
- W54408052 hasConceptScore W54408052C153568844 @default.
- W54408052 hasConceptScore W54408052C185592680 @default.
- W54408052 hasConceptScore W54408052C2778022156 @default.
- W54408052 hasConceptScore W54408052C2778849931 @default.
- W54408052 hasConceptScore W54408052C2780104969 @default.
- W54408052 hasConceptScore W54408052C31903555 @default.
- W54408052 hasConceptScore W54408052C42062724 @default.
- W54408052 hasConceptScore W54408052C523546767 @default.
- W54408052 hasConceptScore W54408052C54355233 @default.
- W54408052 hasConceptScore W54408052C55493867 @default.
- W54408052 hasConceptScore W54408052C59822182 @default.
- W54408052 hasConceptScore W54408052C79029880 @default.
- W54408052 hasConceptScore W54408052C86803240 @default.
- W54408052 hasConceptScore W54408052C89423630 @default.
- W54408052 hasLocation W544080521 @default.
- W54408052 hasOpenAccess W54408052 @default.
- W54408052 hasPrimaryLocation W544080521 @default.
- W54408052 hasRelatedWork W1510110704 @default.
- W54408052 hasRelatedWork W1807143597 @default.
- W54408052 hasRelatedWork W2006651908 @default.
- W54408052 hasRelatedWork W2030330676 @default.
- W54408052 hasRelatedWork W2051306436 @default.
- W54408052 hasRelatedWork W2072591513 @default.
- W54408052 hasRelatedWork W2144507216 @default.
- W54408052 hasRelatedWork W2185358328 @default.
- W54408052 hasRelatedWork W2187972371 @default.
- W54408052 hasRelatedWork W2350936030 @default.
- W54408052 hasRelatedWork W2357066687 @default.
- W54408052 hasRelatedWork W2385232241 @default.
- W54408052 hasRelatedWork W2471356863 @default.
- W54408052 hasRelatedWork W2495388592 @default.
- W54408052 hasRelatedWork W2577392012 @default.
- W54408052 hasRelatedWork W2775512586 @default.
- W54408052 hasRelatedWork W2941811690 @default.
- W54408052 hasRelatedWork W3015448491 @default.
- W54408052 hasRelatedWork W3199558162 @default.
- W54408052 hasRelatedWork W3205694387 @default.
- W54408052 isParatext "false" @default.
- W54408052 isRetracted "false" @default.
- W54408052 magId "54408052" @default.
- W54408052 workType "dissertation" @default.