Matches in SemOpenAlex for { <https://semopenalex.org/work/W54502262> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W54502262 endingPage "206" @default.
- W54502262 startingPage "191" @default.
- W54502262 abstract "Sepsis is a clinical syndrome that arises because of an inappropriate and excessive host inflammatory response. Recent work has demonstrated that this syndrome is also characterized by the development of quantifiable injury in both the lungs and extra-pulmonary organs. This process is clinically expressed as Multiple Organ Dysfunction Syndrome (MODS). Sepsis is also a hypermetabolic state, where tissue O2 needs may be markedly increased. In this context, research has linked the widespread tissue injury typical of this syndrome with an inability to match tissue O2 delivery (D02) with these elevated tissue O2 needs. Thus, the emergence of metabolic dysregulation of tissue O2 availability in sepsis may contribute to the genesis of MODS [1]. For example, mortality in septic patients has been positively correlated with elevated arterial lactates [2] and “pathologic” VO2/DO2 dependency has been demonstrated both in animal [3] and clinical [4] studies of sepsis. As short term increases in arterial lactate and evidence of “pathologic” VO2/ DO2 dependency are regarded as evidence for underlying tissue ischemia [1, 5], it seems probable that MODS complicating sepsis reflects, in whole or in part, the summative effects of tissue injury on a hypoxic-ischemic basis." @default.
- W54502262 created "2016-06-24" @default.
- W54502262 creator A5006828137 @default.
- W54502262 creator A5063775207 @default.
- W54502262 creator A5086266988 @default.
- W54502262 date "1995-01-01" @default.
- W54502262 modified "2023-09-28" @default.
- W54502262 title "Role of RBC Transfusion Therapy in Sepsis" @default.
- W54502262 cites W1265402612 @default.
- W54502262 cites W1973409417 @default.
- W54502262 cites W1992258769 @default.
- W54502262 cites W2000421482 @default.
- W54502262 cites W2017126198 @default.
- W54502262 cites W2027374726 @default.
- W54502262 cites W2027484434 @default.
- W54502262 cites W2039602526 @default.
- W54502262 cites W2046234889 @default.
- W54502262 cites W2048028868 @default.
- W54502262 cites W2048353273 @default.
- W54502262 cites W2049022268 @default.
- W54502262 cites W2051238243 @default.
- W54502262 cites W2052236828 @default.
- W54502262 cites W2055351127 @default.
- W54502262 cites W2064539265 @default.
- W54502262 cites W206524759 @default.
- W54502262 cites W2078210859 @default.
- W54502262 cites W2085041868 @default.
- W54502262 cites W2088354042 @default.
- W54502262 cites W2093139540 @default.
- W54502262 cites W2093357724 @default.
- W54502262 cites W2156967952 @default.
- W54502262 cites W2178915660 @default.
- W54502262 cites W2409900847 @default.
- W54502262 cites W2411982971 @default.
- W54502262 cites W2427485537 @default.
- W54502262 cites W4231274077 @default.
- W54502262 cites W4242806280 @default.
- W54502262 cites W4254984483 @default.
- W54502262 cites W4298273896 @default.
- W54502262 cites W90376605 @default.
- W54502262 doi "https://doi.org/10.1007/978-3-642-79224-3_12" @default.
- W54502262 hasPublicationYear "1995" @default.
- W54502262 type Work @default.
- W54502262 sameAs 54502262 @default.
- W54502262 citedByCount "12" @default.
- W54502262 countsByYear W545022622023 @default.
- W54502262 crossrefType "book-chapter" @default.
- W54502262 hasAuthorship W54502262A5006828137 @default.
- W54502262 hasAuthorship W54502262A5063775207 @default.
- W54502262 hasAuthorship W54502262A5086266988 @default.
- W54502262 hasConcept C126322002 @default.
- W54502262 hasConcept C151730666 @default.
- W54502262 hasConcept C177713679 @default.
- W54502262 hasConcept C2778384902 @default.
- W54502262 hasConcept C2778426790 @default.
- W54502262 hasConcept C2779343474 @default.
- W54502262 hasConcept C2780835948 @default.
- W54502262 hasConcept C2781090800 @default.
- W54502262 hasConcept C71924100 @default.
- W54502262 hasConcept C86803240 @default.
- W54502262 hasConceptScore W54502262C126322002 @default.
- W54502262 hasConceptScore W54502262C151730666 @default.
- W54502262 hasConceptScore W54502262C177713679 @default.
- W54502262 hasConceptScore W54502262C2778384902 @default.
- W54502262 hasConceptScore W54502262C2778426790 @default.
- W54502262 hasConceptScore W54502262C2779343474 @default.
- W54502262 hasConceptScore W54502262C2780835948 @default.
- W54502262 hasConceptScore W54502262C2781090800 @default.
- W54502262 hasConceptScore W54502262C71924100 @default.
- W54502262 hasConceptScore W54502262C86803240 @default.
- W54502262 hasLocation W545022621 @default.
- W54502262 hasOpenAccess W54502262 @default.
- W54502262 hasPrimaryLocation W545022621 @default.
- W54502262 hasRelatedWork W1815707645 @default.
- W54502262 hasRelatedWork W2146690109 @default.
- W54502262 hasRelatedWork W2412142349 @default.
- W54502262 hasRelatedWork W2735761750 @default.
- W54502262 hasRelatedWork W2761728460 @default.
- W54502262 hasRelatedWork W2901303734 @default.
- W54502262 hasRelatedWork W3029035552 @default.
- W54502262 hasRelatedWork W4234924198 @default.
- W54502262 hasRelatedWork W2061918839 @default.
- W54502262 hasRelatedWork W3092478897 @default.
- W54502262 isParatext "false" @default.
- W54502262 isRetracted "false" @default.
- W54502262 magId "54502262" @default.
- W54502262 workType "book-chapter" @default.