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- W54592066 abstract "In the past few years, experiments have elucidated the remarkable mechanism by which phage λ represses is vegetative genes in the lysogenic state by turning off two operons and regulating a third to maintain a constant level of repressor. The control region of λ contains the cI gene that codes for the repressor and is transcribed leftward form the Pr promoter. To the left and to the right of cI are located two operators, OL and OR, that govern the associated promoters PL on the left and PR and Prm on the right. Each operator consists of three repressor binding sites characterized by a 17 base pair sequence recognized by the repressor. The strongest binding site is at the end of the operator nearest the operon it controls and its sequence overlaps that of the promoter. When bound to this site, repressor prevents the RNA polymerase from interacting with the promoter." @default.
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- W54592066 date "1979-01-01" @default.
- W54592066 modified "2023-09-25" @default.
- W54592066 title "ENZYME-DNA AND REPRESSOR-OPERATOR RECOGNITIONS REGULATORY ELEMENTS IN THE IMMUNITY REGIONS OF PHAGES λ AND 434" @default.
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- W54592066 doi "https://doi.org/10.1016/b978-0-08-023175-4.50008-5" @default.
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