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- W54594769 abstract "Like for other side effects oral contraceptives are often blamed for inducing depressive illness. Psychiatric literature and own data permit the following statements: 1. OC's do not induce psychiatric symptoms like depression on a pharmacological basis. 2. There is no preponderance of psychiatric symptoms during pill use. 3. If there is any effect on mood, initiative or affection this is more likely to be mentioned in patients with psychiatric history. 4. The indication for oral contraception in neurotic-psychopathic personalities should be considered seriously. 5. There is a positive secondary psychotropic effect of OC's via improving acne, bleeding irregularities and dysmenorrhoea.Psychotropic effects have been imputed to oral contraceptives (OCs); however, studies with large populations found no depressive episodes caused by OCs. Affective disorders of women such as premenstrual syndrome and postpartum and menopausal depression are well-known. The estrogen and progesterone levels are high during pregnancy, when the risk of emotional disease declines. A study on Marvelon (containing .15 mg of desogestrel and .03 mg of ethinyl estradiol) involving 27,000 women found a history of depression in 3%, but in 90% the symptoms disappeared after OC use. Other studies corroborated the finding that OCs exerted a stabilizing effect on emotional disorders. The overwhelming majority of women without psychiatric anamnesis did not suffer any mood fluctuations under OC use. In a study, 4327 women were interviewed at 3 and 6 months of OC use, and in 45.7% their sense of well-being improved, 30.3% were in a good frame of mind, and 21.2% had a slight deterioration of their sense of well-being. Neurotic and introverted persons tended to attribute affective disorders, weakness of concentration, sleep disturbances, and the avoidance of sex to OCs. With such individuals, OC indication requires particularly strict adherence to rules. The ability of Ocs to improve acne was analyzed when 1785 questionnaires were examined from 1958 women who had used Marvelon. 60% reported improvement of their acne, and 50% of the more severe cases improved. Dysmenorrhea and menstrual cycle disorders improved similarly. Body weight increase in insignificant with modern OCs. OCs exert a positive psychotropic effect through their ability to influence these conditions." @default.
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- W54594769 date "1990-12-01" @default.
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- W54594769 title "[Does the pill have a psychotropic effect?]." @default.
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